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RANK产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
RAK-H5251
Human
Human RANK / TNFRSF11A Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
 
评论(2)
RAK-H5251|Human RANK / TNFRSF11A Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
  1. 182XXXXXXX2
  2. 2人赞
  3. TNFRSF11A只有这个mouse IgG的,试过SDS PAGE的实验,跑出来的灰度还不错,分子量也和官网的差不多。
  4. >
  5. 2019-10-10
RAK-H5251|Human RANK / TNFRSF11A Protein, Mouse IgG2a Fc Tag, low endotoxin (MALS verified)
  1. 185XXXXXXX0
  2. 2人赞
  3. 该产品用于药物发现高通量筛选, Elisa方法包被0.125μg/mlRNAK,可检测2-60ng/ml的RANKL,具有很好的亲和力,用RANK和RANKL建立了稳定的ELISA和REFT筛选体系,可用于抑制剂或者抗体筛选。
  4. 2021-09-05
 

RANK 分子别名

CD265,FEO,LOH18CR1,ODFR,OFE,OPTB7,OSTS,PDB2,RANK,TNFRSF11A,TRANCER,CD265 antigen,ODFROSTS,RANKLOH18CR1,NFKB activator

RANK 分子背景

RANK / TNFRSF11A is a member of the tumor necrosis factor receptor family. RANK / TNFRSF11A shares significant amino acid homology with other members of the TNF R family in its extracellular four cysteine-rich repeats. Functional genomics in mice showed that RANKL (TNFSF11), a member of the TNF ligand superfamily, and RANK (TNFRSF11a), the cognate TNFR family receptor for RANKL, were essential for osteoclastogenesis in vivo. A functional interaction between RANKL, expressed by bone stromal cells of the osteoblast lineage, and RANK, expressed by osteoclast precursors of hematopoietic myeloid lineage, is necessary for osteoclast differentiation, survival, and activation.

RANK 前沿进展

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