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TPBG信息

英文名称:Trophoblast glycoprotein
中文名称:5T4滋养层糖蛋白
靶点别称:Trophoblast glycoprotein,5T4 oncotrophoblast glycoprotein,5T4,TPBG,5T4 oncofetal antigen,M6P1,5T4 oncofetal trophoblast glycoprotein,Wnt-Activated Inhibitory Factor 1,WAIF1,5T4AG,5T4-AG
上市药物数量:0
临床药物数量:4
最高研发阶段:临床三期

TPBG产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
TPG-H82Eb
Human
Biotinylated Human TPBG / 5T4 Protein, His,Avitag
TPG-H52E5
Human
Unconjugated Human TPBG / 5T4 Protein, His,Avitag
 
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TPBG Molecule Synonym Name

TPBG,5T4, M6P1,5T4AG,WAIF1,5T4M6P1,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein

TPBG 分子背景

Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.

TPBG 参考文献

TPBG临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Prostate cancer vaccine, inactivated viral (University of Oxford) 临床阶段不明 牛津大学 前列腺癌 详情
OXB-301 OXB-301; SAR-109659 临床三期 牛津生物医药 肾细胞癌, 前列腺癌 详情
SYD-1875 SYD-1875 临床一期 Synthon Bv 肿瘤 详情
GEN-1044 GEN-1044 临床二期 Genmab 食道癌, 肿瘤, 三阴性乳腺肿瘤, 膀胱癌, 前列腺癌, 子宫肿瘤, 转移癌, 非小细胞肺癌 详情
Naptumomab estafenatox TTS-CD3; ABR-217620 临床二期 Active Biotech 肾细胞癌, 胰腺癌, 非小细胞肺癌 详情

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