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> 【TPBG】
TPBG信息
英文名称：Trophoblast glycoprotein
中文名称：5T4滋养层糖蛋白
靶点别称：Trophoblast glycoprotein，5T4 oncotrophoblast glycoprotein，5T4，TPBG，5T4 oncofetal antigen，M6P1，5T4 oncofetal trophoblast glycoprotein，Wnt-Activated Inhibitory Factor 1，WAIF1，5T4AG，5T4-AG
中文名称：5T4滋养层糖蛋白
靶点别称：Trophoblast glycoprotein，5T4 oncotrophoblast glycoprotein，5T4，TPBG，5T4 oncofetal antigen，M6P1，5T4 oncofetal trophoblast glycoprotein，Wnt-Activated Inhibitory Factor 1，WAIF1，5T4AG，5T4-AG
上市药物数量：0
临床药物数量：6
最高研发阶段：临床一期
临床药物数量：6
最高研发阶段：临床一期
TPBG产品列表
产品库
属性
| 货号 | 物种 | 产品描述 | 蛋白结构 | 纯度 | 活性 |
|---|---|---|---|---|---|
| TPG-H82Eb |
 Human |
Biotinylated Human TPBG / 5T4 Protein, His,Avitag™ |
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| TPG-H52E5 |
Human |
Unconjugated Human TPBG / 5T4 Protein, His,Avitag™ |
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| TPG-C52H3 |
 Cynomolgus / Rhesus macaque |
Cynomolgus / Rhesus macaque TPBG / 5T4 Protein, His Tag |
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| TPG-H5253 |
Human |
Human TPBG / 5T4 Protein, Fc Tag (MALS verified) |
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| TPG-M52H3 |
 Mouse |
Mouse TPBG / 5T4 Protein, His Tag (MALS verified) |
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评论(3)
TPG-H82Eb|Biotinylated Human TPBG / 5T4 Protein, His,Avitag™
- 139XXXXXXX3
- 第二次购买该抗原，上一次做了结合实验，效果不错，这一次开展亲和力检测，希望一切顺利，到货速度很快，抗原包装完好，溶解方法描述清晰，溶解方法简单，溶解度很好，进行实验非常顺利，质量有保障，还会回购
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> - 2022-04-01
0人赞
TPG-H52E5|Unconjugated Human TPBG / 5T4 Protein, His,Avitag™
- 139XXXXXXX3
- 用于抗体筛选工作，目前方法建立顺利进行中，抗原能很好的溶解和包被，提供的技术支持也比较完善，试验中出现的问题都能给予多方面的支持
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> - 2022-04-01
0人赞
TPG-H82Eb|Biotinylated Human TPBG / 5T4 Protein, His,Avitag™
- 138XXXXXXX4
- 一直单位每月都有订你们产品，包装盒安全可靠，运输也很快，来货信息跟实物一致完全准确无误，东西安全可靠，值得信赖，相信今后会更加在市场大阔增更大市场。
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> - 2021-11-11
0人赞
TPBG 分子别名
TPBG,5T4,M6P1,5T4AG,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein
TPBG 分子背景
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.
TPBG 前沿进展
TPBG临床药物信息
| 英文名称 | 研发代码 | 研发阶段 | 公司 | 适应症 | 临床试验 |
|---|---|---|---|---|---|
| Prostate cancer vaccine(inactivated viral)(University of Oxford) | 临床阶段不明 | 牛津大学 | 前列腺癌 | 详情 | |
| OXB-301 | OXB-301; SAR-109659 | 牛津生物医药 | 详情 | ||
| ASN-004 | ASN-004 | Asana Biosciences | 详情 | ||
| SYD-1875 | SYD-1875 | Synthon Bv | 详情 | ||
| PF-06263507 | PF-06263507 | 牛津生物医药 | 详情 | ||
| Naptumomab estafenatox | TTS-CD3; ABR-217620 | Active Biotech | 详情 | ||
| Anti-5T4 CAR-raNK Cell Therapy | 临床一期 | 英百瑞（杭州）生物医药有限公司 | 实体瘤 | 详情 |
