TPBG 靶点蛋白|抗体药物|临床药物信息

TPBG信息

英文名称：Trophoblast glycoprotein
中文名称：5T4滋养层糖蛋白
靶点别称：Trophoblast glycoprotein，5T4 oncotrophoblast glycoprotein，5T4，TPBG，5T4 oncofetal antigen，M6P1，5T4 oncofetal trophoblast glycoprotein，Wnt-Activated Inhibitory Factor 1，WAIF1，5T4AG，5T4-AG

上市药物数量：0
临床药物数量：4
最高研发阶段：临床三期

TPBG产品列表

筛选结果

产品库

在线 (2)

物种

Human (2)

标签

His Tag & Avi Tag (2)

属性

Protein (2)

标记

货号	物种	产品描述	蛋白结构	纯度	活性
TPG-H82Eb	Human	Biotinylated Human TPBG / 5T4 Protein, His,Avitag
TPG-H52E5	Human	Unconjugated Human TPBG / 5T4 Protein, His,Avitag

TPBG Molecule Synonym Name

TPBG,5T4, M6P1,5T4AG,WAIF1,5T4M6P1,WAIF1,5T4 oncofetal antigen,Trophoblast glycoprotein,5T4 oncofetal trophoblast glycoprotein

TPBG 分子背景

Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.

TPBG 参考文献

TPBG临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Prostate cancer vaccine, inactivated viral (University of Oxford)		临床阶段不明	牛津大学	前列腺癌	详情
OXB-301	OXB-301; SAR-109659	临床三期	牛津生物医药	肾细胞癌, 前列腺癌	详情
SYD-1875	SYD-1875	临床一期	Synthon Bv	肿瘤	详情
GEN-1044	GEN-1044	临床二期	Genmab	食道癌, 肿瘤, 三阴性乳腺肿瘤, 膀胱癌, 前列腺癌, 子宫肿瘤, 转移癌, 非小细胞肺癌	详情
Naptumomab estafenatox	TTS-CD3; ABR-217620	临床二期	Active Biotech	肾细胞癌, 胰腺癌, 非小细胞肺癌	详情

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TPBG 重组蛋白