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CA125信息

英文名称:Mucin-16
中文名称:粘蛋白-16
靶点别称:Mucin-16 Short Isoform,Mucin-16 Long Isoform,Ovarian carcinoma antigen CA125,Ovarian cancer-related tumor marker CA125,MUC16,MUC-16,CA-125,Mucin 16, Cell Surface Associated,CA125,CA125 Ovarian Cancer Antigen,Mucin-16,CA-125 Antigen,FLJ14303
上市药物数量:0
临床药物数量:2
最高研发阶段:临床三期

CA125 分子别名

CA125,CA-125,CA125MUC-16,FLJ14303,MUC16,mucin 16,mucin-16

CA125 分子背景

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

CA125 前沿进展

CA125临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Ubamatamab REGN-4018 Regeneron Pharmaceuticals Inc 详情
REGN-5668 REGN-5668 Regeneron Pharmaceuticals 详情
PRGN-3005 PRGN-3005 Precigen 详情
RG-7882 D-4064A; RG-7882; DMUC-4064A 基因泰克 详情
JCAR-020 JCAR-020 临床一期 Memorial Sloan Kettering Cancer Center 实体瘤 详情
Oregovomab B43.13 临床三期 Paladin Pharma 卵巢癌, 腹部肿瘤, 转移性上皮癌, 卵巢上皮癌, 肿瘤, 胰腺癌, 腹膜癌, 输卵管癌, 腺癌 详情

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