CA125 靶点蛋白|抗体药物|临床药物信息

CA125信息

英文名称：Mucin-16
中文名称：粘蛋白-16
靶点别称：Mucin-16 Short Isoform，Mucin-16 Long Isoform，Ovarian carcinoma antigen CA125，Ovarian cancer-related tumor marker CA125，MUC16，MUC-16，CA-125，Mucin 16， Cell Surface Associated，CA125，CA125 Ovarian Cancer Antigen，Mucin-16，CA-125 Antigen，FLJ14303

上市药物数量：0
临床药物数量：2
最高研发阶段：临床三期

CA125产品列表

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在线 (5)

物种

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属性

Protein (5)

标记

货号	物种	产品描述
CA5-H82F4	Human	Biotinylated Human CA125 / MUC16 Protein, Fc,Avitag™
CA5-H82F8	Human	Biotinylated Human CA125 / MUC16 (13810-14451) Protein, Fc,Avitag™
CA5-H52H6	Human	Human CA125 / MUC16 (13810-14451) Protein, His Tag (MALS verified)
CA5-R52H3	Rhesus macaque	Rhesus macaque CA125 / MUC16 (12664-12920) Protein, His Tag (MALS verified)
CA5-R52H6	Rhesus macaque	Rhesus macaque CA125 / MUC16 (13647-14291) Protein, His Tag (MALS verified)

CA125 分子别名

CA125,CA-125,CA125MUC-16,FLJ14303,MUC16,mucin 16,mucin-16

CA125 分子背景

The CA125, also known as the MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. The CA 125 molecule is almost certainly a glycoprotein with a predominance of O-linkages. It is heterogeneous with regard to both size and charge, most likely due to continuous deglycosylation of side chains during its life-span in bodily fluids. It exists as a very large complex (perhaps as much as 4 million daltons) under natural conditions.

CA125 前沿进展

CA125临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
JCAR-020	JCAR-020	临床一期	Memorial Sloan Kettering Cancer Center	卵巢癌	详情
Ubamatamab	REGN-4018	临床二期	Regeneron Pharmaceuticals Inc	卵巢癌, 腹膜癌, 输卵管癌	详情
REGN-5668	REGN-5668	临床二期	Regeneron Pharmaceuticals	卵巢癌, 腹膜癌, 输卵管癌	详情
Oregovomab	B43.13	临床三期	Paladin Pharma	卵巢癌, 转移性上皮癌, 腹部肿瘤, 卵巢上皮癌, 肿瘤, 胰腺癌, 腹膜癌, 输卵管癌, 腺癌	详情
PRGN-3005	PRGN-3005	临床一期	Precigen	卵巢癌, 食道癌, 肉瘤, 腹膜癌, 输卵管癌, 非霍奇金淋巴瘤, 宫颈癌	详情

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CA125