Prolactin 靶点蛋白|抗体药物|临床药物信息

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Protein (2)

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货号	物种	产品描述	蛋白结构	纯度	活性
PRN-H5257	Human	Human Prolactin / PRL Protein, Mouse IgG2a Fc Tag, low endotoxin
PRN-H82F7	Human	Biotinylated Human Prolactin / PRL Protein, Fc,Avitag™

Prolactin 分子别名

PRL,Prolactin

Prolactin 分子背景

Prolactin (gene name PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation, but has pleiotropic effects in both males and females. Prolactin is synthesized as a prohormone. Following cleavage of the signal peptide, the length of the mature hormone is between 194 and 199 amino acids, depending on species. Hormone structure is stabilized by three intramolecular disulfide bonds. Excessive secretion of prolactin - hyperprolactinemia - is a relative common disorder in humans. This condition has numerous causes, including prolactin-secreting tumors and therapy with certain drugs. The prolactin receptor (gene name PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family. Expression of the prolactin receptor is widespread. Each prolactin molecule is thought to bind two receptor molecules

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