Prolactin R 靶点蛋白|抗体药物|临床药物信息

Prolactin R信息

英文名称：Prolactin receptor
中文名称：催乳素受体
靶点别称：PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin

上市药物数量：0
临床药物数量：1
最高研发阶段：临床二期

Prolactin R产品列表

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在线 (2)

物种

Human (2)

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属性

Protein (2)

标记

Unconjugated (2)

货号	物种	产品描述	蛋白结构	纯度	活性
PRP-H5251	Human	Human Prolactin R / PRLR Protein, Fc Tag
PRR-H52Ha	Human	Human Prolactin R / PRLR Protein, His Tag

Prolactin R 分子别名

Prolactin R, PRLR, PRL-R

Prolactin R 分子背景

As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.

Prolactin R 前沿进展

Prolactin R临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
BAY-1158061	BAY-1158061; HMI-115	临床二期	拜耳	脱发, 疼痛, 子宫内膜异位症	详情

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Prolactin R