IL-21分子别名
IL21,Za11,Interleukin-21
IL-21分子背景
Interleukin-21 (IL-21) is a pleiotropic cytokine with actions on a broad range of lymphoid, myeloid and epithelial cells. IL-21 induces a functional programme in CD8+ T cells that leads to enhanced survival, antiviral activity and antitumour activity. IL-21 has a key role in the development of T helper 17 (TH17) cells, which contribute to pathogenesis in a range of inflammatory diseases.