M-CSF 靶点蛋白|抗体药物|临床药物信息

M-CSF信息

英文名称：Macrophage Colony Stimulating Factor 1
中文名称：巨噬细胞集落刺激因子-1
靶点别称：M-CSF，Macrophage colony-stimulating factor 1，CSF-1，CSF1，Colony Stimulating Factor 1，Colony Stimulating Factor 1 (Macrophage)，Macrophage Colony Stimulating Factor 1，Lanimostim，MCSF，Macrophage Colony-Stimulating Factor，MGC31930

上市药物数量：0
临床药物数量：2
最高研发阶段：临床二期

M-CSF产品列表

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在线 (2)

物种

Human (2)

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属性

Protein (2)

标记

货号	物种	产品描述	蛋白结构	纯度	活性
MCF-H5247	Human	Human M-CSF / CSF-1 Protein, His Tag
MCF-H82E6	Human	Biotinylated Human M-CSF / CSF-1 Protein, His,Avitag™

MCF-H5247|Human M-CSF / CSF-1 Protein, His Tag

156XXXXXXX8

5人赞

M-CSF用于开展巨噬细胞的诱导实验，添加M-CSF蛋白诱导PBMC成巨噬细胞，用于开展巨噬细胞的吞噬作用的评价实验。
2021-08-19

MCF-H5247|Human M-CSF / CSF-1 Protein, His Tag

爱思益普

0人赞

to induce monocyte differenration into mycrophage， test cytokine release and surface maker by FACS，the result showed great function in thie induction.
2022-03-11

M-CSF 分子别名

M-CSF,CSF-1,Lanimostim

M-CSF 分子背景

The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.

M-CSF 前沿进展

M-CSF临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Lacnotuzumab	MCS-110	临床二期	诺华制药	腱鞘巨细胞瘤, 骨转移, 色素沉着绒毛结节性滑膜炎, 胃癌, 三阴性乳腺癌, 胰腺癌, 巨细胞瘤, 乳腺癌, 前列腺癌, 子宫内膜癌, 黑色素瘤	详情
PD-360324	PD-360324; PD-0360324	临床二期	辉瑞制药有限公司	肿瘤, 皮肤红斑狼疮, 肺结节病	详情

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M-CSF