LILRB3 分子别名
LILRB3,CD85a,ILT5
LILRB3 分子背景
Leukocyte immunoglobulin-like receptor subfamily B member 3 is also known as LILRB3,ILT-5 or CD85a. LILRB3 plays an role as receptor for class I MHC antigens, which activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3 and LILRA6 represent a pair of inhibitory/activating receptors with identical extracellular domains and unknown ligands. LILRB3 can mediate inhibitory signaling via immunoreceptor tyrosine-based inhibition motifs in its cytoplasmic tail whereas LILRA6 can signal through association with an activating adaptor molecule, FcRγ.
LILRB3 前沿进展
- Bashirova AA., et al., 2014,Immunogenetics.66(1):1-8.
- Huang J., et al., 2010, J Virol. 84(18):9463-71.
- Pfistershammer K., et al., 2009, Blood. 114(11):2323-32.
- Bashirova AA., et al., 2014, Immunogenetics.66(1):1-8.
- Huang J., et al., 2010, J Virol. 84(18):9463-9471.
- Pfistershammer K., et al., 2009, Blood. 114(11):2323-2332.