Recombinant Proteins iso9001 ISO13485
搜索
 > 【IL-13】重组蛋白信息

IL-13信息

英文名称:Interleukin-13
中文名称:白细胞介素-13
靶点别称:Interleukin-13,IL13,Interleukin 13,IL-13,Bronchial Hyperresponsiveness-1 (Bronchial Asthma),Allergic Rhinitis,P600,NC30,MGC116789,MGC116788,BHR1,MGC116786,ALRH
上市药物数量:0
临床药物数量:5
最高研发阶段:临床三期

IL-13产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
IL3-H52H4
Human
Human IL-13 Protein, His Tag
IL3-H5256
Human
Human IL-13 Protein, Fc Tag
IL3-H82E5
Human
Biotinylated Human IL-13 Protein, His,Avitag™
IL3-C52H4
Canine
Canine IL-13 Protein, His Tag
 
评论(0)
 

IL-13 分子别名

IL13,ALRH,BHR1,MGC116786,MGC116788,MGC116789,P600,Interleukin-13

IL-13 分子背景

Interleukin 13 (IL13) is also known as ALRH, BHR1and P600, is a single-chain glycosylated polypeptide, and is a cytokine critical in regulating inflammatory and immune responses. IL13 is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. The functions of IL-13 overlap considerably with those of IL-4, especially with regard to changes induced on hematopoietic cells, but these effects are probably less important given the more potent role of IL-4. IL-13 induces matrix metalloproteinases (MMPs) as part of a mechanism that protects against excessive allergic inflammation that predisposes to asphyxiation. IL-13 induces many features of allergic lung disease, including airway hyperresponsiveness, goblet cell metaplasia and mucus hypersecretion, which all contribute to airway obstruction.

IL-13 参考文献

IL-13临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Dectrekumab/VAK-694 QBX-258 临床二期 诺华制药 淋巴水肿, 哮喘 详情
Romilkimab SUB-33159; SAR-156597 临床二期 赛诺菲 系统性硬皮病, 特发性肺纤维化 详情
Cendakimab ABT-308; RPC-4046 临床二期 Abbott Laoratories 嗜酸性粒细胞性食管炎, 哮喘 详情
Lebrikizumab RG-3637; TNX-650; Anti-IL-13; MILR-1444A; PRO-301444; RO-4909832; RO-5490255; DRM-06; R-3637 临床三期 基因泰克 霍奇金病, 特发性肺纤维化, 皮肤性疾病, 皮炎, 哮喘, 慢性阻塞性肺疾病, 特应性皮炎, 湿疹, 遗传性皮肤病 详情
Tralokinumab CAT-354; BAK-502G9 临床三期 Medimmune Llc 特发性肺纤维化, 哮喘, 溃疡性结肠炎, 特应性皮炎 详情

消息提示

请输入您的联系方式,再点击提交!

确定