CD28H 靶点蛋白|抗体药物|临床药物信息

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在线 (2)

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Human (2)

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Protein (2)

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Unconjugated (2)

货号	物种	产品描述	蛋白结构	纯度	活性
CDH-H5251	Human	Human CD28H / IGPR-1 Protein, Fc Tag (MALS verified)
CDH-H52H3	Human	Human CD28H / IGPR-1 Protein, His Tag

CDH-H5251|Human CD28H / IGPR-1 Protein, Fc Tag (MALS verified)

136XXXXXXX4

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用于HHLA2竞争性抗体筛选，竞争Elisa测试结果比较理想，阳性抗体与候选抗体在0.01-500mg/L区间内可以得到好看的倒S曲线
2022-11-30

CD28H 分子别名

TMIGD2,IGPR1

CD28H 分子背景

CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.

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