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IFN-beta信息

英文名称:Interferon beta
中文名称:干扰素-β
靶点别称
上市药物数量:3
临床药物数量:5
最高研发阶段:批准上市

IFN-beta产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
IFB-H52H3
Human
Human IFN-beta Protein, His Tag
ACRO质量管理体系
 
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IFN-beta 分子别名

IFNB1,Interferon beta,IFN-beta,IFB,IFNB

IFN-beta 分子背景

Human type I interferons (IFNs) are a large subgroup of interferon proteins that help regulate the activity of the immune system. Interferons bind to interferon receptors. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor (IFNAR) that consists of IFNAR1 and IFNAR2 chains. The IFN-β proteins are produced in large quantities by fibroblasts. They have antiviral activity that is involved mainly in innate immune response. Two types of IFN-β have been described, IFN-β1 (IFNB1) and IFN-β3 (IFNB3) (a gene designated IFN-β2 is actually IL-6). IFN-β1 is used as a treatment for multiple sclerosis as it reduces the relapse rate. Furthermore, IFN-β1 can bind to a IFNAR1-IFNAR2 heterodimeric receptor, and can also function with IFNAR1 alone and independently of Jak-STAT pathways.

IFN-beta 前沿进展

IFN-beta上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

IFN-beta临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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