CEACAM-5 靶点蛋白|抗体药物|临床药物信息

CEACAM-5信息

英文名称：Carcinoembryonic antigen related cell adhesion molecule 5
中文名称：癌胚抗原相关细胞粘附分子5
靶点别称：CEA Cell Adhesion Molecule 5，CEACAM5，Meconium antigen 100，CEA，Carcinoembryonic Antigen Related Cell Adhesion Molecule 5，Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5，Carcinoembryonic Antigen，CD66e Antigen，CD66e

上市药物数量：0
临床药物数量：12
最高研发阶段：临床三期

CEACAM-5产品列表

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Protein (10)

标记

货号	物种	产品描述
CE5-H5226	Human	Human CEACAM-5 / CD66e Protein, His Tag (MALS verified)
CE5-H82E0	Human	Biotinylated Human CEACAM-5 / CD66e Protein, His,Avitag™ (MALS verified)
CE5-HF254	Human	FITC-Labeled Human CEACAM-5 / CD66e Protein, His Tag (MALS verified)
CE5-M5253	Mouse	Mouse CEACAM-5 Protein, Fc Tag
CE5-H5253	Human	Human CEACAM-5 Protein, Fc Tag (HPLC verified)
CE5-M52H3	Mouse	Mouse CEACAM-5 Protein, His Tag
CE5-C52H5	Cynomolgus	Cynomolgus CEACAM-5 / CD66e Protein, His Tag (MALS verified)
CE5-HF255	Human	FITC-Labeled Human CEACAM-5 / CD66e Protein, Fc Tag
CE5-H82F6	Human	Biotinylated Human CEACAM-5 / CD66e Protein, Fc,Avitag™
CE5-C82E6	Cynomolgus	Biotinylated Cynomolgus CEACAM-5 / CD66e Protein, His,Avitag™

CE5-H82E0|Biotinylated Human CEACAM-5 / CD66e Protein, His,Avitag™ (MALS verified)

139XXXXXXX2

3人赞

上个月收到了蛋白试用装，使用后效果很好，会继续订购使用的。ACRO公司的服务非常好，有专业的团队上门服务，很满意，会继续使用这个牌子的蛋白和抗体的。
2021-10-12

CE5-M52H3|Mouse CEACAM-5 Protein, His Tag

139XXXXXXX0

1人赞

买回来做蛋白cross实验的，找了全网的销售蛋白公司，终于在acro找到了需要的小鼠蛋白，大公司就是不一样，品种齐全，以前也买你们的蛋白，一直挺稳定，期待这一次的试验结果！
2021-09-29

CE5-H5226|Human CEACAM-5 / CD66e Protein, His Tag (MALS verified)

139XXXXXXX2

1人赞

这款抗体是我们买的第2个抗体，FITC直接标记，染色方便，特异性好。另外我们还订购了Anti-CEA antibody, 还没到货，期待能有更好的结果。
2021-08-06

CEACAM-5 分子别名

CEACAM-5,CD66e,CEA,Meconium antigen 100

CEACAM-5 分子背景

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.

CEACAM-5 前沿进展

CEACAM-5临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
TF 2-targeted cancer therapy	TF-2	临床二期	Immunomedics, Ibc Pharmaceuticals	小细胞肺癌, 皮肤肥大细胞增生症, 乳腺癌, 结直肠癌, 甲状腺瘤, 非小细胞肺癌	详情
NEO-201	NEO-201	临床二期	Precision Biologics, 美国国立癌症研究所	头颈部鳞状细胞癌, 子宫肿瘤, 非小细胞肺癌, 宫颈癌	详情
SGM-101	SGM-101	临床三期	Surgimab	胃癌, 直肠癌, 结肠癌, 胰腺癌, 乳腺癌, 结直肠癌	详情
Labetuzumab govitecan	IMMU-130; hMN-14-SN38	临床二期	Immunomedics, Ibc Pharmaceuticals	直肠癌, 结肠癌, 乳腺癌, 结直肠癌	详情
Carcinoembryonic antigen autologous dendritic cell vaccine (Duke University)		临床二期	杜克大学	肿瘤	详情
Anti-CEA CAR T cell therapy (Shanghai GeneChem)		临床二期	上海吉凯基因医学科技股份有限公司, 空军军医大学西京医院	肝癌, 结直肠癌	详情
Recombinant Saccharomyces cerevisiae-CEA	GI-6207	临床二期	Globeimmune	头颈部鳞状细胞癌, 胰腺癌, 移行细胞癌, 三阴性乳腺肿瘤, 甲状腺髓样癌, 结直肠癌, 鳞状细胞癌, 肝细胞癌, 非小细胞肺癌, 黑色素瘤	详情
Cancer vaccine (BN ImmunoTherapeutics/National Cancer Institute)	CVAC-301; CV-301	临床三期	Therion Biologics	卵巢癌, 胰腺癌, 膀胱癌, 前列腺癌, 乳腺癌, 结直肠癌, 非小细胞肺癌	详情
Cibisatamab	CEA-TCB; RG-7802; RO-6958688; CEA-CD3 TCB	临床二期	罗氏	实体瘤, 结直肠癌, 非小细胞肺癌	详情
Tusamitamab Ravtansine	SAR-408701	临床三期	Immunogen	食道癌, 胃癌, 胰腺癌, 乳腺癌, 非小细胞肺癌, 腺癌	详情
MFE-23-CD3z T cell therapy (Cancer Research Technology)		临床一期	Cancer Research Technology	肿瘤	详情

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CEACAM-5