Recombinant Proteins iso9001 ISO13485
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NS1信息

英文名称:Src homology phosphotyrosyl phosphatase 2
中文名称:蛋白酪氨酸磷酸酶-2
靶点别称:Protein Tyrosine Phosphatase Non-Receptor Type 11,EC:3.1.3.48,SHP-2,PTP2C,Protein-tyrosine phosphatase 2C,PTP-2C,PTP-1D,SH-PTP3,PTPN11,Protein-Tyrosine Phosphatase 1D,SH-PTP2,Noonan Syndrome 1,EC 3.1.3.48,METCDS,SHPTP2,BPTP3,JMML,SHP2,CFC,NS1,Protein Tyro
上市药物数量:0
临床药物数量:4
最高研发阶段:临床二期

NS1产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
NS1-Z5222
Zika virus
Zika virus NS1 Protein, His Tag
NS1-Z82E9
Zika virus
Biotinylated Zika virus NS1 Protein, Avitag,His Tag
 
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NS1 分子别名

NS1

NS1 分子背景

Zika virus (ZIKV) is a member of the virus family Flaviviridae and the genus Flavivirus, transmitted by daytime-active Aedes mosquitoes, such as A. aegypti and A. albopictus. Its name comes from the Zika Forest of Uganda, where the virus was first isolated in 1947. Zika virus is related to dengue, yellow fever, Japanese encephalitis, and West Nile viruses. The infection, known as Zika fever, often causes no or only mild symptoms, similar to a mild form of dengue fever. It is treated by rest. Since the 1950s, it has been known to occur within a narrow equatorial belt from Africa to Asia. As of 2016, the illness cannot be prevented by drugs or vaccines. As of February 2016, there is evidence that Zika fever in pregnant women is associated with abnormal brain development in their fetuses through mother-to-child transmission of the virus, which may result in miscarriage or microcephaly.

NS1 参考文献

NS1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
RLY-1971 RLY-1971 临床一期 Relay Therapeutics 肿瘤 详情
BBP-398 BBP-398; IACS-13909; IACS-15509 临床一期 Navire Pharma Inc 肿瘤 详情
ERAS-601 ERAS-601 临床一期 Erasca Inc 实体瘤 详情
JAB-3312 JAB-3312 临床二期 北京加科思新药研发有限公司 实体瘤, 头颈部鳞状细胞癌, 乳腺癌, 结直肠癌, 胰腺导管癌, 食管鳞状细胞癌, 非小细胞肺癌 详情
RMC-4630 RMC-4630; SAR-442720 临床二期 Revolution Medicines, 赛诺菲 实体瘤, 转移癌 详情
JAB-3068 JAB-3068 临床二期 北京加科思新药研发有限公司 实体瘤, 头颈癌, 头颈部鳞状细胞癌, 食道癌, 食管鳞状细胞癌, 非小细胞肺癌 详情
TNO-155 TNO-155 临床二期 诺华制药 实体瘤, 头颈部鳞状细胞癌, 胃肠道间质瘤, 结直肠癌, 肺癌, 食管鳞状细胞癌, 非小细胞肺癌, 转移癌, 黑色素瘤 详情

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