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LIF信息

英文名称:Leukemia inhibitory factor
中文名称:白血病抑制因子
靶点别称:LIF Interleukin 6 Family Cytokine,D factor,Emfilermin,LIF,Differentiation-stimulating factor,LIF, Interleukin 6 Family Cytokine,Differentiation Inhibitory Activity,Cholinergic Differentiation Factor,Hepatocyte-Stimulating Factor III,Differentiation-Inducing Factor,Melanoma-Derived LPL Inhibitor,Human Interleukin In DA Cells,Leukemia Inhibitory Factor,HILDA,MLPLI,CDF,DIA
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

LIF产品列表

 
评论(1)
LIF-H521b|ActiveMax® Human LIF Protein, Tag Free
  1. 135XXXXXXX8
  2. 1人赞
  3. 购买该蛋白主要作为包被抗原使用,用于间接ELISA的筛选工作,同时也会作为一种刺激因子,刺激不同细胞系用流式去检测,效果不错
  4. >
  5. 2021-12-28
 

LIF 分子别名

LIF,CDF,DIA,HILDA,MLPLI

LIF 分子背景

Leukemia inhibitory factor, or LIF, an interleukin 6 class cytokine, is a protein in cells that affects cell growth and development.Leukemia Inhibitory Factor has several functions such as cholinergic neuron differentiation, control of stem cell pluripotency, bone & fat metabolism, mitogenesis of factor dependent cell lines & promotion of megakaryocyte production in vivo. Removal of LIF pushes stem cells toward differentiation, but they retain their proliferative potential or pluripotency. Therefore LIF is used in mouse embryonic stem cell culture. It is necessary to maintain the stem cells in an undifferentiated state, however genetic manipulation of embryonic stem cells allows for LIF independent growth, notably overexpression of the gene Nanog. LIF is not required for culture of human embryonic stem cells.

LIF 前沿进展

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