CCL6 分子别名
CCL6,SCYA6,C10,MRP-1
CCL6 分子背景
Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC chemokine family, was initially identified as a transcript that is induced in bone marrow cells upon stimulation with GMCSF. CCL6 has only been identified in rodents, A human homologue for mouse CCL6 has not been identified. The mCCL6 cDNA encodes a 116 amino acid residue precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 amino acid residue mature protein. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, where it is strongly induced upon GMCSF (Cat. # GMF-H4214) stimulation. Mouse CCL6 expression was also shown to be strongly induced by IL-4 (Cat. # IL4-H4218) in mouse macrophages and by cytokine IL13 (Cat. # IL3-H4210) in mouse lung. Mouse CCL6 is located on chromosome 11. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.
CCL6 前沿进展
- Orlofsky, et al., 1991, Cell Regul. 2 (5), 403-412.
- Ma., et al., 2004, J Immunol.172(3):1872-81.
- Berger., et al., 1993, DNA Cell Biol. 12 (9), 839-847.
- Kanno M, et al., 2005, J Neuroimmunol. 167(1-2): 72-80.
膜杰作
Star Staining
Aneuro
ComboX
ActiveMax
GENPower
ClinMax
Star Ribbon
