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IL-7信息

英文名称:Interleukin-7
中文名称:白介素7
靶点别称:Interleukin 7,IL7
上市药物数量:0
临床药物数量:2
最高研发阶段:临床一期

IL-7产品列表

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评论(1)
IL7-H4219|Human IL-7 Protein, premium grade
  1. 187XXXXXXX9
  2. 1人赞
  3. 我们用来做ELISA实验的,之前也用过其他厂家的GMP级别的,感觉这个也挺不错的,没有明显差别啊,性价比很高,发货速度又快
  4. >
  5. 2022-11-18
 

IL-7 分子别名

IL7,Interleukin-7

IL-7 分子背景

Interleukin 7 is also known as IL7, IL-7, and is a hematopoietic growth factor secreted by stromal cells in the red marrow and thymus. It is also produced by keratinocytes, dendritic cells, hepatocytes, neurons, and epithelial cells, but is not produced by lymphocytes. IL-7 stimulates the differentiation of multipotent (pluripotent) hematopoietic stem cells into lymphoid progenitor cells, It also stimulates proliferation of all cells in the lymphoid lineage (B cells, T cells and NK cells). It is important for proliferation during certain stages of B-cell maturation, T and NK cell survival, development and homeostasis. IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. IL-7 binds to the IL-7 receptor, a heterodimer consisting of Interleukin-7 receptor alpha and common gamma chain receptor. Il-7 promotes hematological malignacies (acute lymphoblastic leukemia, T cell lymphoma). Elevated levels of IL-7 have also been detected in the plasma of HIV-infected patients. IL-7 as an immunotherapy agent has been examined in many pre-clinical animal studies and more recently in human clinical trials for various malignancies and during HIV infection. IL-7 could also be beneficial in improving immune recovery after allogenic stem cell transplant.

IL-7 前沿进展

IL-7临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Anti-GPC3 chimeric antigen receptor T cell therapy (Hunan Zhaotai Yongren Biotech/Guangdong Zhaotai Invivo Biomedicine) 临床一期 湖南昭泰涌仁生物科技有限公司, 广东昭泰体内生物医药科技有限公司 鳞状细胞癌, 肝细胞癌 详情
CT0181 CT-0181 临床一期 科济药业控股有限公司 肝细胞癌 详情

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