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uPAR信息

英文名称:Urokinase plasminogen activator surface receptor
中文名称:尿激酶型纤溶酶原激活物表面受体
靶点别称:Monocyte activation antigen Mo3,U-PAR,uPAR,CD87,Urokinase-Type Plasminogen Activator (UPA) Receptor,URKR,U-Plasminogen Activator Receptor Form 2,CD87 Antigen,Plasminogen Activator, Urokinase Receptor,MO3
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

uPAR 分子别名

uPAR,PLAUR,CD87,MO3

uPAR 分子背景

Urokinase plasminogen activator surface receptor (U-PAR) is also known as PLAUR, Monocyte activation antigen Mo3, CD antigen CD87. PLAUR contains three UPAR/Ly6 domains. U-PAR is expressed in neurons of the rolandic area of the brain (at protein level) and is also expressed in the brain. PLAUR / CD87 interacts with MRC2, SRPX2 and SORL1. PLAUR / UPAR acts as a receptor for urokinase plasminogen activator and plays a role in localizing and promoting plasmin formation. U-PAR mediates the proteolysis-independent signal transduction activation effects of U-PA.

uPAR 前沿进展

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