IL-4 靶点蛋白|抗体药物|临床药物信息

IL-4信息

英文名称：Interleukin-4
中文名称：白细胞介素-4
靶点别称：MGC79402，B-cell stimulatory factor 1，Lymphocyte stimulatory factor 1，IL4，Interleukin 4，B_cell Stimulatory Factor 1，B Cell Growth Factor 1，Binetrakin，Pitrakinra，BSF-1，IL-4，Interleukin 4 Variant 2，BCGF-1，BCGF1，BSF1，Interleukin-4

上市药物数量：0
临床药物数量：4
最高研发阶段：临床二期

IL-4产品列表

筛选结果

产品库

物种

标签

属性

标记

货号	物种	产品描述
IL4-H4218	Human	Human IL-4 Protein, premium grade
IL4-H82E0	Human	Biotinylated Human IL-4 Protein, Avitag™,His Tag (MALS verified)
IL4-M52H5	Mouse	Mouse IL-4 Protein, His Tag
IL4-C5259	Cynomolgus	Cynomolgus IL-4 Protein, Fc Tag (MALS verified)
IL4-H52H9	Human	Human IL-4 Protein, His Tag (MALS verified)
CRS-A004	Human	Human Interleukin-4(IL-4) ELISA Kit
CEA-C003	Human	ClinMax™ Human IL-4 ELISA Kit
EP-132	Human	IL-4 [Biotinylated] : IL-4Rα Inhibitor Screening ELISA Kit

ACROBiosystems提供将现有的目录Non-GMP级别（RUO或Premium级别）蛋白产品快速转化为GMP级别的升级服务，也可以从零开始为您提供GMP级别蛋白从头定制化开发服务>>点击立即咨询GMP级别蛋白产品定制服务~

IL4-H82E0|Biotinylated Human IL-4 Protein, Avitag™,His Tag (MALS verified)

177XXXXXXX7

4人赞

购买蛋白为human-il4，作为octect亲和力测试用。
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2022-02-19

IL4-H82E0|Biotinylated Human IL-4 Protein, Avitag™,His Tag (MALS verified)

139XXXXXXX3

3人赞

用于抗体筛选工作，抗原包被效果良好，目前实验顺利进行中，提供的技术支持也比较完善，试验中出现的问题都能给予多方面的支持
2022-01-05

IL4-H4218|Human IL-4 Protein, premium grade

156XXXXXXX8

2人赞

购买该蛋白用于巨噬细胞诱导，开展巨噬细胞相关功能性验证实验，在添加M-CSF和IL-4的情况下，可以诱导PBMC和THP1细胞分化成为具有免疫抑制作用的M2型巨噬细胞。
2021-08-19

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IL-4 分子别名

IL4,BCGF1,BSF1

IL-4 分子背景

Interleukin-4, is a cytokine that induces differentiation of naive helper T cells (Th0 cells to Th2 cells). In the presence of IL-4 and IL-13, cytokines that are produced in a Th-2 type response, particularly during allergy and parasitic infections, macrophages become differentially activated, And this cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. Recently, researcher found that the cytokine IL-4 plays a key role in development of innate CD8+ T cells in the thymus of several gene-deficient mouse strains, including Itk, KLF2, CBP and Id3, without previous exposure to antigen.

IL-4 前沿进展

IL-4临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Dectrekumab/VAK-694	QBX-258	临床二期	诺华制药	淋巴水肿, 哮喘	详情
OCH-NCNP1	OCH-NCNP1	临床二期	庆应义塾大学	多发性硬化, 克罗恩病	详情
DMT-210	DMT-200; DMT-210; DMT-220; SIG-990		Signum Dermalogix		详情
AIR-645	AIR-645; ISIS-369645		Ionis Pharmaceuticals Inc		详情
Romilkimab	SUB-33159; SAR-156597		赛诺菲		详情
GSK-2434735	GSK-2434735		葛兰素史克		详情
VAK-694	VAK-694; NVP-VAK-694		诺华制药		详情
Berdazimer sodium	NVN1000-SB206; MAP3-NONOate - SB-206; SB-019; NVN-1000-SB-206-Novan; SB-206		Novan		详情

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会议一览

IL-4