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项目名称 适应症 项目阶段 合作需求
BLL202201 实体瘤 Phase Ⅰ 寻求项目转让或者合作开发
BMS21010 肺癌、肝癌、胃癌、前列腺癌、宫颈癌、前列腺癌、肝癌等肿瘤 细胞株筛选阶段 寻求项目转让或者合作开发(公司处于创业期,寻求外部合作快速推进研发)

TIM-3产品列表

 
评论(2)
TM3-H5229|Human TIM-3 / HAVCR2 Protein, His Tag (MALS verified)
  1. 182XXXXXXX6
  2. 0人赞
  3. 购买此产品主要用于单克隆抗体制备,产品纯度高,性能稳定,储存方便,最开始的亲和力检测就拿到了很完美的实验结果,趋势很棒,相信后续能拿到最满意的实验结果。
  4. >
  5. 2022-06-12
TM3-H82E7|Biotinylated Human TIM-3 / HAVCR2 Protein, Avitag™,His Tag (MALS verified)
  1. 139XXXXXXX3
  2. 0人赞
  3. 到货速度很快,抗原包装完好,溶解方法描述清晰,溶解方法简单,溶解度很好,进行实验非常顺利,质量有保障,还会回购
  4. 2022-06-16
 

TIM-3 分子别名

HAVCR2,TIM3,TIMD3,FLJ14428,KIM3

TIM-3 分子背景

Hepatitis A virus cellular receptor 2 is also known as HAVCR2, FLJ14428,  KIM3, TIM3, TIMD3, is a member of the TIM family of immune regulating molecules with one Ig-like V-type domain and a Ser/Thr-rich mucin stalk. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. HAVCR2 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice. HAVCR2 regulates macrophage activation. Inhibits T-helper type 1 lymphocyte (Th1)-mediated auto- and alloimmune responses and promotes immunological tolerance. May be also involved in T-cell homing. Dysregulation of the HAVCR2-galectin-9 pathway could underlie chronic autoimmune disease states in human, such as multiple sclerosis.

TIM-3 前沿进展

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