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TIM-1信息

英文名称:T-cell immunoglobulin mucin receptor 1
中文名称:T细胞免疫球蛋白粘蛋白受体-1
靶点别称:CD365 Antigen,HAVCR,TIMD1,T-cell immunoglobulin mucin receptor 1,TIMD-1,TIM-1,CD365,TIM1,HAVCR1,Hepatitis A Virus Cellular Receptor 1,Kidney Injury Molecule 1,T-Cell Immunoglobulin Mucin Family Member 1,T-Cell Membrane Protein 1,KIM-1,KIM1,TIM,T Cell Immunoglobin Domain And Mucin Domain Protein 1,HAVcr-1,T-Cell Immunoglobulin And Mucin Domain-Containing Protein 1
上市药物数量:0
临床药物数量:1
最高研发阶段:终止

TIM-1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
KI1-H52H3
Human
Human TIM-1 / HAVCR1 Protein, His Tag (MALS verified)
 
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TIM-1 分子别名

HAVCR1,KIM1,TIM1,TIMD1

TIM-1 分子背景

Hepatitis A virus cellular receptor 1 is also known as HAVCR1, HAVCR, KIM1, TIM, TIM1, TIMD1, is widely expressed with highest levels in kidney and testis. The protein encoded by HAVCR1 gene is a membrane receptor for both human hepatitis A virus (HHAV) and TIMD4. The encoded protein may be involved in the moderation of asthma and allergic diseases. The reference genome represents an allele that retains a MTTVP amino acid segment that confers protection against atopy in HHAV seropositive individuals. Three transcript variants encoding the same protein have been found for this gene. HAVCR1 may play a role in T-helper cell development, the regulation of asthma and allergic diseases and in kidney injury and repair. In case of human hepatitis A virus (HHAV) infection, functions as a cell-surface receptor for the virus.

TIM-1 前沿进展

TIM-1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
CDX-014 CDX-014; CR 014-vcMMAE 安进, Curagen 详情

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