Serpin F1 靶点蛋白|抗体药物|临床药物信息

Serpin F1信息

英文名称：Pigment epithelium-derived factor
中文名称：色素上皮衍生因子
靶点别称：Testis Tissue Sperm-Binding Protein Li 70n，SERPINF1，Serpin F1，Cell proliferation-inducing gene 35 protein，EPC-1，Serpin Family F Member 1，Proliferation-Inducing Protein 35，OI12，Serpin Peptidase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，Alpha-2 Antiplasmin，PIG35，Serine (Or Cysteine) Proteinase Inhibitor， Clade F (Alpha-2 Antiplasmin， Pigment Epithelium Derived Factor)， Member 1，OI6

上市药物数量：0
临床药物数量：1
最高研发阶段：临床二期

Serpin F1产品列表

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产品库

在线 (1)

物种

Human (1)

标签

His Tag (1)

属性

Protein (1)

标记

Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
SE1-H5221	Human	Human Serpin F1 / PEDF Protein, His Tag

Serpin F1 分子别名

SERPINF1,Serpin F1,PEDF,PIG35,EPC-1

Serpin F1 分子背景

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Serpin F1 前沿进展

Serpin F1临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
DVC1-0401	DVC1-0401	临床二期	Kyushu University, Id Pharma	色素性视网膜炎	详情
BRM-421	BRM-421		全福生物科技股份有限公司		详情

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Serpin F1