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Serpin F1信息

英文名称:Pigment epithelium-derived factor
中文名称:色素上皮衍生因子
靶点别称:Testis Tissue Sperm-Binding Protein Li 70n,SERPINF1,Serpin F1,Cell proliferation-inducing gene 35 protein,EPC-1,Serpin Family F Member 1,Proliferation-Inducing Protein 35,OI12,Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium De
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

Serpin F1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
SE1-H5221
Human
Human Serpin F1 / PEDF Protein, His Tag
 
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Serpin F1 分子别名

SERPINF1,Serpin F1,PEDF,PIG35,EPC-1

Serpin F1 分子背景

erpin F1 (SERPINF1) is also known as Pigment epithelium-derived factor (PEDF), Cell proliferation-inducing gene 35 protein (PIG35). Serpin F1 belongs to the serpin family. Serpin F1 is expressed in quiescent cells. PEDF has a variety of functions including antiangiogenic, antitumorigenic, and neurotrophic properties. Endothelial cell migration is inhibited by SERPINF1/ PEDF. PEDF / SERPINF1 suppresses retinal neovascularization and endothelial cell proliferation. PEDF is also responsible for apoptosis of endothelial cells either through the p38 MAPK pathway or through the FAS/FASL pathway. PEDF also displays neurotrophic functions.

Serpin F1 参考文献

Serpin F1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
DVC1-0401 DVC1-0401 临床一期 Kyushu University, Id Pharma 色素性视网膜炎 详情

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