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IL-1 alpha信息

英文名称:Interleukin-1 alpha
中文名称:白细胞介素-1α
靶点别称
上市药物数量:1
临床药物数量:5
最高研发阶段:批准上市

IL-1 alpha 分子别名

IL1A,IL-1 ALPHA,IL1F1,IL1α

IL-1 alpha 分子背景

Interleukin-1 alpha (IL1a) is also known as IL-1A, IL1, IL1-ALPHA,IL1F1,and is a cytokine of the interleukin-1 family. IL1a possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. IL-1α is constitutively produced by epithelial cells. It is found in substantial amounts in normal human epidermis and is distributed in a 1:1 ratio between living epidermal cells and stratum corneum.The constitutive production of large amounts of IL-1α precursor by healthy epidermal keratinocytes interfere with the important role of IL-1α in immune responses, assuming skin as a barrier, which prevents the entry of pathogenic microorganisms into the body. In vitro, IL-1α possesses biological effect on cells in the picomolar to femtomolar range. In vivo, Shortly after an onset of an infection into organism, IL-1α activates a set of immune system response processes.

IL-1 alpha 前沿进展

IL-1 alpha上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验

IL-1 alpha临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验

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