ROR2 靶点蛋白|抗体药物|临床药物信息

ROR2信息

英文名称：Tyrosine-protein kinase transmembrane receptor ROR2
中文名称：蛋白酪氨酸激酶跨膜受体ROR2
靶点别称：EC:2.7.10.1，ROR2，NTRKR2，Receptor Tyrosine Kinase Like Orphan Receptor 2，Tyrosine-Protein Kinase Transmembrane Receptor ROR2，Neurotrophic Tyrosine Kinase， Receptor-Related 2，Neurotrophic Tyrosine Kinase Receptor-Related 2，Receptor Tyrosine Kinase-Like Orphan Receptor 2，EC 2.7.10.1，BDB1，BDB

上市药物数量：0
临床药物数量：2
最高研发阶段：临床二期

ROR2产品列表

筛选结果

产品库

在线 (4)

物种

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属性

Protein (4)

标记

货号	物种	产品描述
RO2-H5251	Human	Human ROR2 / NTRKR2 Protein, Fc Tag
RO2-H52E5	Human	Human ROR2 / NTRKR2 Protein, His Tag
RO2-H82E3	Human	Biotinylated Human ROR2 / NTRKR2 Protein, His,Avitag™
RO2-M5253	Mouse	Mouse ROR2 / NTRKR2 Protein, Fc Tag

RO2-H52E5|Human ROR2 / NTRKR2 Protein, His Tag

187XXXXXXX1

2人赞

购买该抗原用于phage筛选目的抗体，经过实验验证，得到很好的筛选阳性结果。也可用来做BLI分析，在humanFc生物传感器上加载的human单克隆抗体，可以有效结合。在elisa blocking assay上,相较于另一家同类产品背景非常干净，后续筛选都用的这个蛋白，已经拿到lead
2022-11-18

RO2-H52E5|Human ROR2 / NTRKR2 Protein, His Tag

153XXXXXXX5

1人赞

使用这款同家族蛋白，Human ROR2-His（RO2-H52E5），用途是基于ELISA的同家族蛋白的区分，在小鼠血清效价检测与杂交瘤上清阶段，都可以用这个蛋白来表征抗体库的性质。
2022-06-05

RO2-H52E5|Human ROR2 / NTRKR2 Protein, His Tag

188XXXXXXX9

0人赞

This homologous protein, Human ROR2-His (RO2-H52E5), is used to distinguish homologous proteins based on ELISA, and can be used to characterize the antibody library in both mouse serum titer detection and hybridoma supernatant phase.
2023-04-14

ROR2 分子别名

ROR2,NTRKR2

ROR2 分子背景

Tyrosine-protein kinase transmembrane receptor ROR2 is also known as Neurotrophic tyrosine kinase, receptor-related 2 (NTRKR2), which belongs to the protein kinase superfamily and Tyr protein kinase family and ROR subfamily. ROR2 is a homodimer protein, which can binds YWHAB or interact with WTIP. ROR2 may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development.

ROR2 前沿进展

ROR2临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Ozuriftamab Vedotin	CAB-ROR2-ADC; CAB-ADC; CAB-ROR2; BA-3021; HTBA-3021	临床二期	Bioatla	实体瘤, 卵巢癌, 头颈癌, 头颈部鳞状细胞癌, 三阴性乳腺癌, 黑色素瘤, 非小细胞肺癌, 转移癌	详情
CCT301-59	CCT301-59	临床二期	Bioatla, F1 Oncology	实体瘤, 肾细胞癌, 胃癌, 胰腺癌, 膀胱癌, 肉瘤	详情

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ROR2

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ROR2产品列表

ROR2 分子别名

ROR2 分子背景

ROR2 前沿进展

ROR2临床药物信息

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