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MBL信息

英文名称:Mannose-binding protein C
中文名称:甘露糖结合蛋白C
靶点别称:MBP1,COLEC1,Mannose-binding protein C,Mannose-binding lectin,MBP-C,MBL2,Mannose Binding Lectin 2,MBL,Mannose-Binding Lectin 2, Soluble (Opsonic Defect),Mannose-Binding Lectin (Protein C) 2, Soluble,Mannan-Binding Protein,Mannan-Binding Lectin,HSMBPC,MBL2D
上市药物数量:0
临床药物数量:0
最高研发阶段:终止

MBL产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
MBL-H5220
Human
Human MBL Protein, His Tag
 
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MBL 分子别名

MBL,MBL2,MBP1,MBP-C,Collectin-1,COLEC1,HSMBPC,MBL2D,MBPD

MBL 分子背景

Mannose-binding lectin (MBL) is also known as mannose-binding protein, mannan-binding protein (MBP), Mannose-binding protein C, Collectin-1 (COLEC1), MBL2, which belongs to the class of collectins in the C-type lectin superfamily. MBL contains one C-type lectin domain and one collagen-like domain. MBL has an oligomeric structure (400-700 kDa), built of subunits that contain three presumably identical peptide chains of about 30 kDa each. MBL is calcium-dependent lectin involved in innate immune defense. MBL binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. MBL binds to late apoptotic cells. MBL may bind DNA.

MBL 前沿进展

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