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KIR2DL3信息

英文名称:Killer cell immunoglobulin-like receptor 2DL3
中文名称:杀伤细胞免疫球蛋白样受体2DL3
靶点别称:P58.2 MHC Class-I Specific NK Receptor,MHC Class I NK Cell Receptor,CD158b2 Antigen,KIR-K7b,KIR-K7c,KIR2DS5,CD158b,KIR2DL,NKAT2A,NKAT2B,GL183,NKAT,P58,Receptors, KIR2DL3,Cl-6,Killer Cell Immunoglobulin-Like Receptor Two Domains Long Cytoplasmic Tail 3,Natural Killer Cell Inhibitory Receptor KIR2DL3,Natural Killer Associated Transcript 2,p58.2 MHC class-I-specific NK receptor,Natural killer-associated transcript 2,NKAT-2,NKAT2,p58 natural killer cell receptor clone CL-6,Killer inhibitory receptor
上市药物数量:0
临床药物数量:1
最高研发阶段:临床二期

KIR2DL3产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
KI3-H5258
Human
Human KIR2DL3 / CD158b2 / NKAT-2 Protein, Fc Tag (MALS verified)
 
评论(1)
KI3-H5258|Human KIR2DL3 / CD158b2 / NKAT-2 Protein, Fc Tag (MALS verified)
  1. 136XXXXXXX4
  2. 0人赞
  3. 作为对照用于对比检测高亲和力融合蛋白突变体对其受体的亲和力差异,最终以acro该产品binding affinity为基准筛选到提高10倍亲和力的突变体9个
  4. 2022-08-31
 

KIR2DL3 分子别名

CD158b2

KIR2DL3 分子背景

Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3) is also known as CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, MHC class I NK cell receptor, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, CD158b2 and KIR2DL3, which is a single-pass type I membrane protein and belongs to the immunoglobulin superfamily.KIR2DL3 is a receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). KIR2DL3 can inhibit the activity of NK cells thus preventing cell lysis.

KIR2DL3 前沿进展

KIR2DL3临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Lirilumab IPH-21; NN-1975; IPH-2101; IPH-2102; BMS-986015 临床二期 诺和诺德制药 实体瘤, 白血病, 头颈部鳞状细胞癌, 淋巴细胞性白血病, 阴燃多发性骨髓瘤, 霍奇金病, 肿瘤, 多发性骨髓瘤, 膀胱癌, 急性髓细胞样白血病, 非霍奇金淋巴瘤, 慢性淋巴细胞白血病 详情

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