Recombinant Proteins iso9001 ISO13485
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 > 【Jagged 1】重组蛋白信息

Jagged 1信息

英文名称:Protein jagged-1
中文名称:Jagged-1蛋白
靶点别称:AHD,AWS,AGS,Jagged-1 Protein,Jagged1,Protein jagged-1,JAG1,Jagged 1,JAGL1,Alagille Syndrome,CD339,AGS1,Jagged Canonical Notch Ligand 1,DCHE,hJ1,CD339 Antigen
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

Jagged 1产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
JA1-H52H9
Human
Human Jagged 1 /JAG1 /CD339 Protein, His Tag
 
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Jagged 1 分子别名

CD339,JAG1,Jagged1,hJ1,JAGL1

Jagged 1 分子背景

Protein jagged-1 (JAG1) is also known as Jagged1, hJ1, JAGL1 and CD339, which is a single-pass type I membrane protein containing one DSL domain and 15 EGF-like domains. JAG1 is widely expressed in adult and fetal tissues,the expression of JAG1 is up-regulated in cervical squamous cell carcinoma and also expressed in bone marrow cell line HS-27a.JAG1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. JAG1 is involved in early and late stages of mammalian cardiovascular development. JAG1 inhibits myoblast differentiation by similarity and enhances fibroblast growth factor-induced angiogenesis (in vitro).

Jagged 1 参考文献

Jagged 1临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
AMG-430 AMG-430 临床一期 安进 囊性纤维化, 慢性阻塞性肺疾病 详情

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