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 > 【IL-17E】

IL-17E信息

英文名称:Interleukin-25
中文名称:白介素25
靶点别称:IL17E,IL-25,IL-17E,Interleukin-17E,Interleukin 17E,Interleukin 25
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

IL-17E 分子别名

IL-17E,IL-25,Interleukin-25

IL-17E 分子背景

Interleukin 25 (IL25) is also known as Interleukin-17E (IL-17E), is a distinct member of the IL17 cytokine family comprised of at least six members sharing a conserved cysteine-knot structure but divergent at the N-terminus. IL-25 is secreted by type 2 helper T cells (Th2) and mast cells. IL25 can induce NF-κB activation, and stimulate the production of IL8. Both this cytokine and IL17B are ligands for the cytokine receptor IL17RB. IL-25 induces the production of other cytokines, including IL-4, IL-5 and IL-13 in multiple tissues, which stimulate the expansion of eosinophils. This cytokine is an important molecule controlling immunity of the gut and has been implicated in chronic inflammation associated with the gastrointestinal tract. IL-25 can kill some types of breast cancer cells.

IL-17E 前沿进展

IL-17E临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
XKH-001(Xinkanghe Biomedical) XKH-001 临床一期 苏州鑫康合生物医药科技有限公司, 北京鑫康合生物医药科技有限公司 哮喘, 炎性疾病 详情

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