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IL-1 RAcP信息

英文名称:Interleukin-1 receptor accessory protein
中文名称
靶点别称:Interleukin-1 receptor 3,IL-1RAcP,IL-1 receptor accessory protein,IL-1R-3,C3orf13,Interleukin 1 Receptor Accessory Protein,IL1R3,Interleukin-1 Receptor Accessory Protein Beta,IL-1R3
上市药物数量:0
临床药物数量:2
最高研发阶段:临床二期

IL-1 RAcP产品列表

产品库
物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
ILP-H5225
Human
Human IL-1 RAcP / IL-1 R3 Protein, His Tag
ILP-H5256
Human
Recombinant Human IL-1 RAcP / IL-1 R3 / C3orf13 Protein
 
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IL-1 RAcP 分子别名

IL1RAP,IL-1RAcP,C3orf13,IL1R3

IL-1 RAcP 分子背景

Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.

IL-1 RAcP 前沿进展

IL-1 RAcP临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
GSK3903371 GSK3903371 临床阶段不明 葛兰素史克 肿瘤 详情
Nidanilimab CAN-04 临床二期 Lund University Foundation 头颈部鳞状细胞癌, 胰腺癌, 三阴性乳腺肿瘤, 移行细胞癌, 乳腺癌, 结直肠癌, 胰腺导管癌, 非小细胞肺癌, 黑色素瘤 详情

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