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HSP90AA1信息
英文名称：Heat shock protein HSP 90-alpha
中文名称：热休克蛋白90α家族A类成员1
靶点别称：Heat Shock Protein 90kDa Alpha (Cytosolic)， Class A Member 1，Heat Shock 90kDa Protein 1， Alpha，Heat Shock 90kD Protein 1， Alpha，HSP 86，HSP90A，HSPC1，Heat Shock Protein 90kDa Alpha Family Class A Member 1，Epididymis Secretory Sperm Binding Protein Li 65p，Epididymis Luminal Secretory Protein 52，Heat Shock 90kD Protein 1， Alpha-Like 4，Heat Shock 90kD Protein， Alpha-Like 4，HEL-S-65p，FLJ31884，HSPCAL1，HSPCAL4，HSP89A，HSP90N，Hsp103，Hsp89，Hsp90，EL52，HSPN，LAP2，Heat shock protein HSP 90-alpha，HSP86，LPS-asso
中文名称：热休克蛋白90α家族A类成员1
靶点别称：Heat Shock Protein 90kDa Alpha (Cytosolic)， Class A Member 1，Heat Shock 90kDa Protein 1， Alpha，Heat Shock 90kD Protein 1， Alpha，HSP 86，HSP90A，HSPC1，Heat Shock Protein 90kDa Alpha Family Class A Member 1，Epididymis Secretory Sperm Binding Protein Li 65p，Epididymis Luminal Secretory Protein 52，Heat Shock 90kD Protein 1， Alpha-Like 4，Heat Shock 90kD Protein， Alpha-Like 4，HEL-S-65p，FLJ31884，HSPCAL1，HSPCAL4，HSP89A，HSP90N，Hsp103，Hsp89，Hsp90，EL52，HSPN，LAP2，Heat shock protein HSP 90-alpha，HSP86，LPS-asso
上市药物数量：0
临床药物数量：1
最高研发阶段：临床前
临床药物数量：1
最高研发阶段：临床前
HSP90AA1产品列表
| 货号 | 物种 | 产品描述 | 蛋白结构 | 纯度 | 活性 |
|---|---|---|---|---|---|
| HS1-H513x |
 Human |
Human HSP90AA1 / HSP 90-alpha Protein, with N-GST Tag |
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HSP90AA1 分子别名
HSP90AA1,HSP90A,HSP 86,HSP86,HSPC1,HSPCA,EL52,HSP89A,HSP90N,HSPCAL1,HSPCAL4,HSPN,Hsp89,Hsp90,LAP2
HSP90AA1 分子背景
Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
HSP90AA1 前沿进展
HSP90AA1临床药物信息
| 英文名称 | 研发代码 | 研发阶段 | 公司 | 适应症 | 临床试验 |
|---|---|---|---|---|---|
| Pimitespib | TAS-116 | 大鹏药品工业株式会社, 大冢制药株式会社 | 详情 |
