膜杰作
Star Staining
ViruStop
Aneuro
ComboX
ActiveMax
GENPower
ClinMax
> 【GITR】
GITR信息
英文名称：Glucocorticoid-induced tumor necrosis factor receptor-related protein
中文名称：糖皮质激素诱导的肿瘤坏死因子受体相关蛋白
靶点别称：TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
中文名称：糖皮质激素诱导的肿瘤坏死因子受体相关蛋白
靶点别称：TNFRSF18，TNF Receptor Superfamily Activation-Inducible Protein，ENERGEN，GITR-D，Tumor Necrosis Factor Receptor Superfamily Member 18，CD357 Antigen，Activation-Inducible TNFR Family Receptor，AITR，CD357，GITR，Glucocorticoid-Induced TNFR-Related Protein，Tumor Necrosis Factor Receptor Superfamily， Member 18，TNF Receptor Superfamily Member 18
上市药物数量：0
临床药物数量：8
最高研发阶段：临床二期
临床药物数量：8
最高研发阶段：临床二期
GITR产品列表
产品库
属性
评论(1)
GIR-H5228|Human GITR / TNFRSF18 Protein, His Tag (MALS verified)
- 151XXXXXXX3
- 使用Acro的产品很久了，不管是产品还是技术，每次都是有问题及时解决。用过的GITR蛋白，做过SPR实验，6个浓度梯度做，拟合曲线也很不错，数据也是达到我的预期，希望以后还是合作愉快。
- 2019-09-27
4人赞
GITR 分子别名
AITR,GITR,TNFRSF18,CD357
GITR 分子背景
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
GITR 前沿进展
GITR临床药物信息
| 英文名称 | 研发代码 | 研发阶段 | 公司 | 适应症 | 临床试验 |
|---|---|---|---|---|---|
| BMS-986156 | BMS-986156 | 临床二期 | 百时美施贵宝 | 实体瘤 | 详情 |
| MK-4166 | MK-4166 | 临床一期 | Merck & Co Inc | 实体瘤, 胶质母细胞瘤 | 详情 |
| Anti-GITR antibody (BMS) | 临床一期 | 百时美施贵宝 | 肿瘤 | 详情 | |
| GWN-323 | GWN-323 | 临床一期 | 诺华制药 | 实体瘤, 淋巴瘤 | 详情 |
| TRX-518 | TRX-518 | 临床二期 | Tolerx | 卵巢癌, 乳腺癌, 前列腺癌 | 详情 |
| ASP-1951 | PTZ-522; ASP-1951 | 临床一期 | Potenza Therapeutics | 实体瘤 | 详情 |
| Ragifilimab | INCAGN-1876; INCAGN-01876 | 临床二期 | 安帝君斯公司, 路德维格癌症研究所 | 转移癌 | 详情 |
| REGN-6569 | REGN6569; REGN-6569 | 临床一期 | Regeneron Pharmaceuticals | 头颈部鳞状细胞癌 | 详情 |
