FABP6 靶点蛋白|抗体药物|临床药物信息

FABP6信息

英文名称：Bile acid binding protein
中文名称：胆汁酸结合蛋白
靶点别称：ILBP3，Gastrotropin，Intestinal Bile Acid-Binding Protein，Fatty Acid Binding Protein 6， Ileal，Intestinal 15 KDa Protein，I-BABP，Fatty Acid-Binding Protein 6，I-BALB，I-BAP，ILLBP，Ileal Bile Acid Binding Protein，ILBP，Fatty Acid Binding Protein 6，Illeal Lipid-Binding Protein，Ileal Lipid-Binding Protein，I-15P，FABP6，GT

上市药物数量：2
临床药物数量：2
最高研发阶段：批准上市

FABP6产品列表

筛选结果

产品库

在线 (1)

物种

Human (1)

标签

His Tag (1)

属性

Protein (1)

标记

Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
FA6-H5141	Human	Human FABP6 Protein, His Tag

FABP6 分子别名

FABP6,ILBP,ILLBP,Gastrotropin,GT,I-15P,I-BABP,I-BALB,I-BAP

FABP6 分子背景

Fatty acid-binding protein 6 (FABP6), is also known as Intestinal bile acid-binding protein (I-BABP), Ileal lipid-binding protein (ILBP), Intestinal 15 kDa protein (I-15P), Gastrotropin (GT). FABP6 is a cytoplasm protein which belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. Isoform 2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Ileal protein FABP6 stimulates gastric acid and pepsinogen secretion. FABP6 seems to be able to bind to bile salts and bilirubins. Isoform 2 of FABP6 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.

FABP6 前沿进展

FABP6上市药物信息

英文名称	中文名称	研发代码	研发阶段	公司	最早商品名	最早批准国家	最早适应症	最早批准公司	最早批准日期	适应症	临床试验
Colestipol Hydrochloride	盐酸考来替泊		批准上市	辉瑞制药有限公司	Colestid	United States	高脂血症	Pharmacia & Upjohn	1977-04-04	高脂血症	详情
Colesevelam Hydrochloride	盐酸考来维仑	GT31-104HB; GT-31104; GT31-104	批准上市	美国健赞公司	CholestaGel, Welchol, Colestagel	EU	高胆固醇血症	Genzyme Europe Bv	2000-05-26	非酒精性脂肪肝, 二型糖尿病, 高胆固醇血症, 多发性骨髓瘤, 杂合子家族性高胆固醇血症, II型高脂蛋白血症, 高脂血症	详情

FABP6临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
A-3384	A-3384		Albireo		详情
Colesevelam (Ironwood)	IW-3718		Ironwood		详情

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FABP6