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 > 【FABP6】

FABP6信息

英文名称:Bile acid binding protein
中文名称:胆汁酸结合蛋白
靶点别称:ILBP3,Gastrotropin,Intestinal Bile Acid-Binding Protein,Fatty Acid Binding Protein 6, Ileal,Intestinal 15 KDa Protein,I-BABP,Fatty Acid-Binding Protein 6,I-BALB,I-BAP,ILLBP,Ileal Bile Acid Binding Protein,ILBP,Fatty Acid Binding Protein 6,Illeal Lipid-Binding Protein,Ileal Lipid-Binding Protein,I-15P,FABP6,GT
上市药物数量:2
临床药物数量:2
最高研发阶段:批准上市

FABP6产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
FA6-H5141
Human
Human FABP6 Protein, His Tag
 
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FABP6 分子别名

FABP6,ILBP,ILLBP,Gastrotropin,GT,I-15P,I-BABP,I-BALB,I-BAP

FABP6 分子背景

Fatty acid-binding protein 6 (FABP6), is also known as Intestinal bile acid-binding protein (I-BABP), Ileal lipid-binding protein (ILBP), Intestinal 15 kDa protein (I-15P), Gastrotropin (GT). FABP6 is a cytoplasm protein which belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. Isoform 2 of FABP6 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 of FABP6 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Ileal protein FABP6 stimulates gastric acid and pepsinogen secretion. FABP6 seems to be able to bind to bile salts and bilirubins. Isoform 2 of FABP6 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.

FABP6 前沿进展

FABP6上市药物信息

英文名称 中文名称 研发代码 研发阶段 公司 最早商品名 最早批准国家 最早适应症 最早批准公司 最早批准日期 适应症 临床试验
Colestipol Hydrochloride 盐酸考来替泊 批准上市 辉瑞制药有限公司 Colestid United States 高脂血症 Pharmacia & Upjohn 1977-04-04 高脂血症 详情
Colesevelam Hydrochloride 盐酸考来维仑 GT31-104HB; GT-31104; GT31-104 批准上市 美国健赞公司 CholestaGel, Welchol, Colestagel EU 高胆固醇血症 Genzyme Europe Bv 2000-05-26 非酒精性脂肪肝, 二型糖尿病, 高胆固醇血症, 多发性骨髓瘤, 杂合子家族性高胆固醇血症, II型高脂蛋白血症, 高脂血症 详情

FABP6临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
A-3384 A-3384 Albireo 详情
Colesevelam (Ironwood) IW-3718 Ironwood 详情

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