登录 | 注册    关注公众号  
微信公众号
搜索
 > 【DNAM-1】

DNAM-1信息

英文名称:CD226 antigen
中文名称
靶点别称:DNAX accessory molecule 1,DNAM-1,T Lineage-Specific Activation Antigen 1 Antigen,PTA1,DNAX Accessory Molecule-1,Adhesion Glycoprotein,TLiSA1,DNAM1,CD226 Molecule,Platelet And T Cell Activation Antigen 1
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

DNAM-1分子别名

DNAM1,CD226,PTA1

DNAM-1分子背景

DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.

消息提示

请输入您的联系方式,再点击提交!

确定