Cyclophilin B 分子别名
PPIB,CYPB,PPIase B,CYP-S1
Cyclophilin B 分子背景
Peptidyl-prolyl cis-trans isomerase B (PPIB or PPIase B) is also known as Cyclophilin B (CYPB), Rotamase B, S-cyclophilin (SCYLP), is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum, which belongs to the cyclophilin-type PPIase family and PPIase B subfamily. PPIB / CYPB contains one PPIase cyclophilin-type domain. PPIases accelerate the folding of proteins and catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Cyclophilin B 前沿进展
- Arber S., et al, 1992, J. Cell Biol. 116:113-125.
- Chi A., et al., 2006, J. Proteome Res. 5:3135-3144.
- Zhang, Jianying, et al., 2003, J. Biol. Chem. (United States) 278 (9): 7459–68.