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 > 【Complement Component C5a】重组蛋白信息

Complement Component C5a信息

英文名称:C5a anaphylatoxin chemotactic receptor
中文名称:过敏毒素C5a趋化受体
靶点别称:Receptor, Anaphylatoxin C5a,C5a-R,Complement Component 5 Receptor 1 (C5a Ligand),C5a Anaphylatoxin Chemotactic Receptor,C5AR,Complement C5a Receptor 1,Complement Component 5a Receptor 1,C5a Anaphylatoxin Chemotactic Receptor 1,C5a Anaphylatoxin Receptor,C
上市药物数量:0
临床药物数量:2
最高研发阶段:临床三期

Complement Component C5a产品列表

 
评论(2)
C5A-H5116|Human Complement Component C5a Protein, Tag Free
  1. 176XXXXXXX3
  2. 1人赞
  3. 因为实验室用的蛋白种类比较多,所以Acro,Sino,R&D的产品都有在用,因为Acro到货最快,所以一直都是我们的第一选择,产品质量也很赞。但有时候做实验也会发现不同厂家的产品会有差异,同样的氨基酸序列,同样的浓度,很想咨询一下这种差异来源是什么呢?每次实验前买好几种产品真的很麻烦 ̄□ ̄||
  4. 2020-07-01
C5A-H5116|Human Complement Component C5a Protein, Tag Free
  1. 151XXXXXXX5
  2. 1人赞
  3. 从Acro订购太多蛋白了,这一款给我印象深刻,不说试用装很大方地送我做预实验,我所需的蛋白他们还会开发不同种属的,节省了我很多时间,最重要的,相关蛋白,他家不止做结合实验,还会把相关活性实验也进行检测,而且还分享给客户,那是相当周全了。愿所有的蛋白你家都有。
  4. 2019-09-26
 

Complement Component C5a Molecule Synonym Name

C5a,Complement Component 5a

Complement Component C5a 分子背景

Human Complement Component C5a (C5a) is also known as C5,and is a protein fragment released from complement component C5.,is a potent chemotactic factor for human peripheral blood neutrophils and monocytes, and is believed to play an important role in a number of inflammatory conditions. There are several functions in the below: C5a is an anaphylatoxin, causing the release of histamine from mast cells; C5a is effective leukocyte chemoattractants, causing the accumulation of white blood cells, especially neutrophil granulocytes, at sites of complement activation; C5a activates white blood cells by increasing avidity for white blood cell integrins and upregulating the Lipoxygenase pathway for arachidonic acid metabolism; C5a is a powerful inflammatory mediator, and seems to be a key factor in the development of pathology of many inflammatory diseases involving the complement system; C5a modulates balance between activating versus inhibitory IgG Fc receptors on leukocytes, thereby enhancing autoimmune response.

Complement Component C5a 参考文献

Complement Component C5a临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Avdoralimab NN-8210; IPH-5401; Anti-C5aR-215; NNC-0215-0384 临床二期 诺和诺德制药 肿瘤, 类风湿关节炎, 新型冠状病毒肺炎, 炎性疾病 详情
Avacopan CCX-168 临床三期 Chemocentryx 抗中性粒细胞胞浆抗体相关性血管炎, 免疫球蛋白a肾病, 血管炎, 膜增生性肾小球肾炎, 化脓性汗腺炎 详情

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