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CD98信息

英文名称:L-type amino acid transporter 1
中文名称:L-型氨基酸转运蛋白-1
靶点别称:D16S469E,Solute Carrier Family 7 (Cationic Amino Acid Transporter, Y+ System), Member 5,LAT1,SLC7A5,Y+ System Cationic Amino Acid Transporter,4F2LC,4F2 LC,Large Neutral Amino Acid-Transporter 1,Large Neutral Amino Acids Transporter Small Subunit 1,Solute Carrier Family 7 Member 5,HLAT1,CD98LC,CD98,Sodium-Independent Neutral Amino Acid Transporter LAT1,L-Type Amino Acid Transporter 1,4F2 Light Chain,E16,Solute Carrier Family 7 (Amino Acid Transporter Light Chain, L System), Member 5,MPE16,Integra
上市药物数量:0
临床药物数量:7
最高研发阶段:临床二期

CD98产品列表

货号 物种 产品描述 蛋白结构 纯度 活性
CD8-H5247
Human
Human CD98 Protein, His Tag (MALS verified)
CD8-HF248
Human
FITC-Labeled Human CD98 Protein, His Tag
ACRO质量管理体系
 
评论(3)
CD8-H5247|Human CD98 Protein, His Tag (MALS verified)
  1. 188XXXXXXX9
  2. 1人赞
  3. Acro试剂包装特别完整,冷链到位,物流速度极快。 ACRO是我唯一信任的品牌。 我比较过不同厂家的蛋白,他家的蛋白活性和重复性都很好。 冻干粉状态良好,coa信息全面。 非常感谢acro。 希望acro能够发展得越来越好。 感谢acro,合作愉快!
  4. 2023-09-26
CD8-H5247|Human CD98 Protein, His Tag (MALS verified)
  1. 188XXXXXXX9
  2. 0人赞
  3. Acro reagent packaging is particularly complete, the cold chain is in place, and the logistics speed is extremely fast. ACRO is the only brand I trust. I have compared proteins from different manufacturers, and the one from his family has good activity and repeatability. The freeze-dried powder is in good condition, and the information on the coa is comprehensive. Thank you very much to acro. I hope acro will develop better and better. Thanks acro, happy cooperation!
  4. 2023-06-02
CD8-H5247|Human CD98 Protein, His Tag (MALS verified)
  1. 131XXXXXXX6
  2. 0人赞
  3. 购买该公司的抗原主要是用于小鼠免疫,进而筛选特异性抗体。之前有购买过其他厂家的其他抗体,稳定性和抗原识别表位,并不符合预期。虽然Acro抗原价格相对较高,但是保证实验可靠性和重复性,还是非常靠谱的选择!
  4. 2023-10-13
 

CD98分子别名

SLC3A2,CD98,4F2,4F2HC,4T2HC,CD98HC,MDU1,NACAE

CD98分子背景

CD antigen CD98 is also known as 4F2 cell-surface antigen heavy chain (4F2hc), 4F2 heavy chain antigen, Solute carrier family 3 member 2 (SLC3A2), Lymphocyte activation antigen 4F2 large subunit, is a single-pass type I I membrane protein which belongs to the SLC3A transporter family.. SLC3A2 / CD98 is expressed ubiquitously in all tissues tested with highest levels detected in kidney, placenta and testis and weakest level in thymus. SLC3A2 / CD98 is required for the function of light chain amino-acid transporters and also involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. CD98 involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A5 or SLC7A8, CD98 involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals.

CD98临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Nanvuranlat JPH-203SBECD; JPH-203; KYT-0353 临床二期 J-Pharma 胆管癌 详情
R-OKY-034F R-OKY-034F 临床二期 大阪大学, Japan Agency For Medical Research And Development 胰腺癌 详情
[18F]AA-7 [18F]AA-7 临床阶段不明 大阪市立大学, Institute Physical Chemical Research (Riken), Nagase Medicals 胶质瘤 详情
O-18F-fluoroethyl-L-tyrosine 18F-FET; FET-[18F]; TLX101-CDx; TLX-101-CDx 临床二期 Advanced Imaging Projects 肉瘤, 乳腺癌, 胶质瘤, 淋巴瘤 详情
QBS-10072-S QBS10072S; QBS72S; QBS-72-S; QBS-10072-S 临床二期 Novotech (Australia) Pty Ltd 乳腺癌, 宫颈癌, 舌肿瘤, 黑色素瘤, 肺癌, 脑转移, 胸腺瘤, 泌尿系肿瘤, 结直肠癌, 星形细胞瘤, 前列腺癌, 脑癌, 肝癌, 胆管上皮癌, 肉瘤, 膀胱癌, 间皮组织肿瘤, 胰腺癌, 胃癌, 食道癌, 肾肿瘤, 头颈癌, 卵巢癌 详情
131I-ACD-101 TLX101; TLX-101; 131I-ACD-101; 131I-IPA; 131I-TX-101 临床二期 Telix Pharmaceuticals Ltd 胶质母细胞瘤, 肿瘤, 乳腺癌 详情
NBQ72S NBQ72S 临床一期 南通本草八达医药科技香港有限公司, 精鼎医药研究开发(上海)有限公司 实体瘤 详情

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