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> 【CD27】
CD27信息
英文名称：CD27 antigen
中文名称：CD27抗原
靶点别称：CD27 antigen，Tumor necrosis factor receptor superfamily member 7，CD27L receptor，CD27，CD27 Molecule，T-Cell Activation Antigen CD27，TNFRSF7，T14，T Cell Activation Antigen S152，S152. LPFS2，S152，Tp55，Tumor Necrosis Factor Receptor Superfamily， Member 7
中文名称：CD27抗原
靶点别称：CD27 antigen，Tumor necrosis factor receptor superfamily member 7，CD27L receptor，CD27，CD27 Molecule，T-Cell Activation Antigen CD27，TNFRSF7，T14，T Cell Activation Antigen S152，S152. LPFS2，S152，Tp55，Tumor Necrosis Factor Receptor Superfamily， Member 7
上市药物数量：0
临床药物数量：4
最高研发阶段：临床二期
临床药物数量：4
最高研发阶段：临床二期
CD27产品列表
评论(1)
CD7-H5254|Human CD27 / TNFRSF7 Protein, Fc Tag (HPLC verified)
- 139XXXXXXX3
- 使用百普赛斯的蛋白进行大分子之间的相互作用，可以取得较好的实验效果，拥有批间差异小，实验重复性好的优点，值得信赖
- 2022-06-25
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CD27 分子别名
CD27,TNFRSF7,S152,T14,Tp55
CD27 分子背景
CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
CD27 前沿进展
CD27临床药物信息
| 英文名称 | 研发代码 | 研发阶段 | 公司 | 适应症 | 临床试验 |
|---|---|---|---|---|---|
| Anti-CD27 monoclonal antibody (Aduro Biotech) | BION-1402 | 临床一期 | Aduro Biotech | 肿瘤 | 详情 |
| Boserolimab | MK-5890 | Merck & Co Inc | 详情 | ||
| LOR-S03 | CDX-527 | Celldex Therapeutics | 详情 | ||
| Varlilumab | CDX-1127 | 临床二期 | Celldex Therapeutics | 膀胱癌, 黑色素瘤, 慢性淋巴细胞白血病, 非小细胞肺癌, 泌尿生殖道肿瘤, 肺癌, 胶质瘤, 淋巴瘤, 泌尿系肿瘤, 星形细胞瘤, 前列腺癌, 套细胞淋巴瘤, 泌尿系疾病, 卵巢癌, 少突神经胶质瘤, 三阴性乳腺肿瘤, 肾脏疾病, 肿瘤, 胶质母细胞瘤, 肾细胞癌, 头颈部鳞状细胞癌, 头颈癌, 肾肿瘤, 实体瘤, B-细胞淋巴瘤 | 详情 |
