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CD200信息

英文名称:OX-2 membrane glycoprotein
中文名称:OX-2膜糖蛋白
靶点别称:My033,CD200,CD200 Antigen,Antigen Identified By Monoclonal Antibody MRC OX-2,MOX1,OX-2 Membrane Glycoprotein,OX-2,MRC,CD200 Molecule,MOX2
上市药物数量:0
临床药物数量:2
最高研发阶段:临床一期

CD200 分子别名

CD200,MOX1,MOX2,MRC,OX-2,My033

CD200 分子背景

CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.

CD200 前沿进展

CD200临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
CD-200-AR-L CD-200-AR-L; hP-1-A-8 临床一期 University Of Minnesota 胶质母细胞瘤 详情
Samalizumab ALXN-6000 Alexion Pharmaceuticals Inc, The Leukemia & Lymphoma Society 详情

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