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IL-24信息

英文名称:Interleukin 24
中文名称:白细胞介素24
靶点别称:ST16,Interleukin-24,IL24,MDA-7,Suppression of tumorigenicity 16 protein,IL-24,Interleukin 24,Suppression Of Tumorigenicity 16 (Melanoma Differentiation),Melanoma Differentiation-Associated Gene 7 Protein,IL-4-Induced Secreted Protein,MDA7,Melanoma Differentiation Association Protein 7,Melanocyte-Associated Mda-7,IL10B,C49A,FISP,MOB5,Mob-5
上市药物数量:0
临床药物数量:1
最高研发阶段:临床一期

IL-24产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
IL4-H52H4
Human
Human IL-24 Protein, His Tag (BLI verified)
ACRO质量管理体系
 
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IL-24分子别名

Interleukin-24,IL-24,Melanoma differentiation-associated gene 7 protein,MDA-7,Suppression of tumorigenicity 16 protein,IL24,MDA7,ST16

IL-24分子背景

Interleukin-24 (IL-24, also known as melanoma differentiation-associated gene-7) belongs to the family of IL-10-related cytokines, which includes IL-10, -19, -20, -22, -24 and -26. Interleukin 24 signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. Upon binding to its receptors, IL-24 induces rapid activation of Stat-1 and Stat-3 transcription factors, which appear to play a role in cell survival and proliferation . Structurally and functionally, IL-24 is highly conserved across species.IL-24 has been shown to possess cancer-specific apoptosis-inducing activity, and has therefore been suggested as a potential anti-cancer agent.

IL-24临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
Interleukin 24 gene therapy (MultiVir) Ad-IL-24; Ad-IL24 临床一期 Multivir Inc 头颈癌, 黑色素瘤 详情

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