Cathepsin B 靶点蛋白|抗体药物|临床药物信息

Cathepsin B信息

英文名称：Cathepsin B
中文名称：组织蛋白酶B
靶点别称：EC 3.4.22，EC:3.4.22.1，RECEUP，Cathepsin B，Amyloid Precursor Protein Secretase，Epididymis Secretory Sperm Binding Protein，Cathepsin B1，Cysteine Protease，EC 3.4.22.1，CPSB，APPS，APP secretase，CTSB

上市药物数量：0
临床药物数量：1
最高研发阶段：临床二期

Cathepsin B产品列表

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在线 (2)

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His Tag (2)

属性

Protein (2)

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Unconjugated (2)

货号	物种	产品描述	蛋白结构	纯度	活性
CTB-H5222	Human	Human Cathepsin B / CTSB Protein, His Tag (active enzyme, MALS verified)
CTB-M52H9	Mouse	Mouse Cathepsin B / CTSB Protein, His Tag (active enzyme, MALS verified)

CTB-H5222|Human Cathepsin B / CTSB Protein, His Tag (active enzyme, MALS verified)

181XXXXXXX0

6人赞

酶切linker效果很好，可实现较为高效和具有特异性的酶切作用，而且产品纯度比较高，稳定性好，实验的可重复性还挺好的，总之产品满意。
2022-03-18

CTB-H5222|Human Cathepsin B / CTSB Protein, His Tag (active enzyme, MALS verified)

183XXXXXXX6

2人赞

很喜欢arco家的产品，每次购买不仅会送一些礼品券而且评论还会送咖啡，这家公司不仅品味好，人品还好。买的CathepsinB产品还会有详细的介绍，最重要的是它还有PPT介绍，对实验性人星太友好了
2022-12-09

CTB-H5222|Human Cathepsin B / CTSB Protein, His Tag (active enzyme, MALS verified)

178XXXXXXX2

1人赞

1样品很稳定，活性很好 2、样品蛋白容易溶解 3 活性好！4，存储稳定性特别好，非常好的感受 5 ，物流特别快，隔天到 6 多年的选择
2022-04-21

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Cathepsin B分子别名

CTSB,CPSB,APPS

Cathepsin B分子背景

Cathepsin B (CTSB) is also known as APP secretase (APPS) and CPSB, is an enzymatic protein belonging to the peptidase C1 family. Cathepsin B / CTSB is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme. The catalytic activity of Cathepsin B / APPS contains: Hydrolysis of proteins with broad specificity for peptide bonds; Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L); In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides. As a thiol protease, cathepsin B / CPSB is believed to participate in intracellular degradation and turnover of proteins and has also been implicated in tumor invasion and metastasis. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors.

Cathepsin B临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Osugacestat	AL-101(BMS); BMS-906024	临床二期	百时美施贵宝, 葛兰素史克	肿瘤, 三阴性乳腺癌, 腺样囊性癌, 前体T-淋巴母细胞性淋巴瘤白血病	详情

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Cathepsin B

Cathepsin B信息

Cathepsin B产品列表

Cathepsin B分子别名

Cathepsin B分子背景

Cathepsin B临床药物信息

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