Plectin 分子别名
Plectin,PLTN,PCN,HD1,Hemidesmosomal protein 1,PLEC1
Plectin 分子背景
Interlinks intermediate filaments with microtubules and microfilaments and anchors intermediate filaments to desmosomes or hemidesmosomes. Could also bind muscle proteins such as actin to membrane complexes in muscle. May be involved not only in the filaments network, but also in the regulation of their dynamics. Structural component of muscle. Isoform 9 plays a major role in the maintenance of myofiber integrity.
Plectin 前沿进展