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Angiogenin产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
ANN-H5149
Human
Human Angiogenin / RNASE5 Protein, His Tag
 
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Angiogenin 分子别名

ALS9,ANG,Angiogenin,angiogenin, ribonuclease, RNase A family, 5,EC 3.1.27,EC:3.1.27.-

Angiogenin 分子背景

Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo

Angiogenin 前沿进展

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