OSMR 靶点蛋白|抗体药物|临床药物信息

OSMR信息

英文名称：Oncostatin-M-specific receptor subunit beta
中文名称：抑瘤素-M-特异性受体β亚基
靶点别称：IL-31R-beta，IL-31RB，Interleukin-31 receptor subunit beta，IL-31 receptor subunit beta，IL-31R subunit beta

上市药物数量：0
临床药物数量：1
最高研发阶段：临床二期

OSMR产品列表

筛选结果

产品库

在线 (2)

物种

标签

His Tag (2)

属性

Protein (2)

标记

Unconjugated (2)

货号	物种	产品描述	蛋白结构	纯度	活性
OSR-C52H9	Cynomolgus	Cynomolgus OSMR beta Protein, His Tag (MALS verified)
OSR-H52H9	Human	Human OSMR beta Protein, His Tag (MALS verified)

OSMR 分子别名

Oncostatin-M-specific receptor subunit beta,Interleukin-31 receptor subunit beta,IL-31 receptor subunit beta,IL-31R subunit beta,IL-31R-beta,IL-31RB,OSMR,OSMRB

OSMR 分子背景

Oncostatin-M-specific receptor subunit beta(OSMRB) alos know as Interleukin-31 receptor subunit beta (IL-31RB), is an alternative subunit (OSMRβ) for an OSM receptor complex (a heterodimer of gp130 and OSMRβ), that is activated by OSM but not by LIF. OSMR beta associates with the low affinity OSM·gp130 complex to form a high affinity heterodimeric receptor that is capable of transducing OSM-specific signaling events.

OSMR 前沿进展

OSMR临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
Vixarelimab	BIIB-069; KPL-716	临床二期	百健	瘙痒症, 慢性荨麻疹, 银屑病, 神经性皮炎, 扁平苔藓, 痒疹	详情

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OSMR