BTLA 靶点蛋白|抗体药物|临床药物信息

BTLA信息

英文名称：B- and T-lymphocyte attenuator
中文名称：B和T淋巴细胞衰减因子
靶点别称：BTLA，B- and T-lymphocyte attenuator，B- and T-lymphocyte-associated protein，B And T Lymphocyte Associated，CD272 Antigen，BTLA1，CD272

上市药物数量：0
临床药物数量：3
最高研发阶段：临床二期

BTLA产品列表

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产品库

在线 (13)

物种

标签

属性

Protein (13)

标记

货号	物种	产品描述
BTA-M52E2	Mouse	Mouse BTLA Protein, His Tag
BTA-H5255	Human	Human BTLA (31-134) Protein, Fc Tag
BTA-H5256	Human	Human BTLA (31-150) Protein, Fc Tag (MALS verified)
BTA-M5253	Mouse	Mouse BTLA Protein, Fc Tag (MALS verified)
BTA-H82F8	Human	Biotinylated Human BTLA (31-134) Protein, Fc,Avitag™
BTA-H82F3	Human	Biotinylated Human BTLA (31-150) Protein, Fc,Avitag™ (MALS verified)
BTA-H5258	Human	Human BTLA (31-150) Protein, Mouse IgG2a Fc Tag (MALS verified)
BTA-H52H3	Human	Human BTLA (31-150) Protein, His Tag (MALS verified)
BTA-H82E5	Human	Biotinylated Human BTLA (31-150) (M105V, G138S, V148M) Protein, His,Avitag™ (MALS verified)
BTA-H52H5	Human	Human BTLA (31-150) (M105V, G138S, V148M) Protein, His Tag (MALS verified)
BTA-H82F5	Human	Biotinylated Human BTLA (31-150) (M105V, G138S, V148M) Protein, Fc,Avitag™ (MALS verified)
BTA-H82E4	Human	Biotinylated Human BTLA (31-150) Protein, His,Avitag™ (MALS verified)
BTA-H5254	Human	Human BTLA (31-150) (M105V, G138S, V148M) Protein, Fc Tag (MALS verified)

BTLA 分子别名

BTLA,CD272

BTLA 分子背景

B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM.

BTLA 前沿进展

BTLA临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
ANB-032	ANB-032	临床一期	Anaptysbio Inc	炎性疾病	详情
LY-3361237	LY-3361237	临床二期	礼来制药, 桑福德－伯纳姆·普利比斯医学发现研究所	系统性红斑狼疮, 银屑病	详情
Tifcemalimab	TAB-004; JS-004	临床二期	上海君实生物医药科技股份有限公司	实体瘤, 头颈癌, 头颈部鳞状细胞癌, 肾细胞癌, 尿路上皮癌, 鼻咽癌, 肺癌, 淋巴瘤, 转移癌, 黑色素瘤	详情

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BTLA