Complement C2 靶点蛋白|抗体药物|临床药物信息

Complement C2信息

英文名称：Complement C2
中文名称：补体C2
靶点别称：C3/C5 convertase

上市药物数量：0
临床药物数量：1
最高研发阶段：临床二期

Complement C2产品列表

筛选结果

产品库

在线 (2)

物种

标签

His Tag (2)

属性

Protein (2)

标记

Unconjugated (2)

货号	物种	产品描述	蛋白结构	纯度	活性
CO2-H52H7	Human	Human Complement C2 Protein, His Tag (MALS verified) (active enzyme)
CO2-C52H8	Cynomolgus	Cynomolgus Complement C2 Protein, His Tag (active enzyme)

Complement C2 分子别名

C2,Complement C2,Complement Component C2

Complement C2 分子背景

C2 is a major histocompatibility complex class-III protein. Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. The lectin (LP) and classical (CP) pathways are two of the three main activation cascades of the complement system. These pathways start with recognition of different pathogen- or danger-associated molecular patterns and include identical steps of proteolytic activation of complement component C4, formation of the C3 proconvertase C4b2, followed by cleavage of complement component C2 within C4b2 resulting in the C3 convertase C4b2a.

Complement C2 前沿进展

Complement C2临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
ARGX-117	ARGX-117	临床二期	Argenx BV	周围神经系统疾病, 运动神经元病, 新型冠状病毒肺炎	详情

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Complement C2