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Laminin 221 E8产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
LA2-H5269
Human
Human Laminin 221 E8 Protein, Fc Tag (MALS verified)
 
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Laminin 221 E8 分子别名

Laminin 221 E8

Laminin 221 E8 分子背景

Laminin-221 (LM221) takes multiple roles as a scaffold to store cells, growth factors and cytokines and is the most likely expressed cardiac laminin that maintains physiological activities of myocytes. Laminin 221-E8 consists of the C-terminal end of the alpha 2, beta 2, and gamma 1 chains. Previous study has confirmed that the laminin-221 heterotrimer (α2β2γ1) could bind integrin α7X1 and α7X2. Latest research indicated that the administration of LM221 enhanced accumulation of smooth muscle actin (SMA) and isolectin B4 (ILB4) double-positive cells to the damaged area and contributed to the improvement of cardiac function.

Laminin 221 E8 前沿进展

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