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Siglec-7 | J chain产品列表

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物种
属性
货号 物种 产品描述 蛋白结构 纯度 活性
SI7-H5259
Human
Human Siglec-7&J chain Pentamer Protein, IgM Fc Tag&His Tag
 
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Siglec-7 | J chain 分子别名

CDw328,D-siglec,A79 membrane protein,p75,Adhesion inhibitory receptor molecule 1,AIRM-1

Siglec-7 | J chain 分子背景

Siglec-7 is a member of the human CD33‐related Siglec receptor. The extracellular region of Siglec‐7 is characterized by an N‐terminal V‐set Ig domain that can bind sialic acid and two C2‐set Ig domains. The cytoplasmic tail of Siglec‐7 has one immune‐receptor tyrosine‐based inhibitory motif (ITIM) and one ITIM‐like motif. Siglec-7 is considered as a sialic acid-dependent immunoreceptor with inhibitory potential and expressed predominantly on human NK cells, monocytes and a small subset of CD8+ T cells.

Siglec-7 | J chain 前沿进展

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