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Endoglin产品列表

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货号 物种 产品描述 蛋白结构 纯度 活性
ENN-H52H9
Human
Human Endoglin / CD105 Protein, His Tag
 
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Endoglin 分子别名

Endoglin,CD105,ENG,END

Endoglin 分子背景

Endoglin (ENG), endothelial glycoprotein, also known as CD105, is a coreceptor of the transforming growth factor-β (TGFβ) family signaling complex, which is highly expressed on endothelial cells and plays a key role in angiogenesis. It regulates the responses associated with binding to transforming growth factor β1 egg (Activin-A), bone morphogenetic protein 2 (BMP-2), and bone morphogenetic protein 7 (BMP-7). Endoglin may be involved in autosomal dominant disease, such as hereditary hemorrhagic telangiectasia 1 (HHT1). Circulating soluble ENG is also elevated in pulmonary arterial hypertension(PAH) and is proposed to be a biomarker for the prognosis of group I PAH patients.

Endoglin 前沿进展

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