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 > 【CXCL4】

CXCL4信息

英文名称:Platelet factor 4
中文名称:血小板因子4
靶点别称:PF-4,C-X-C motif chemokine 4,CXCL4
上市药物数量:0
临床药物数量:0
最高研发阶段:临床前

CXCL4产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
CX4-H52H9
Human
Human CXCL4 / PF4 Protein, His Tag
ACRO质量管理体系
 
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CXCL4分子别名

PF4,CXCL4,MGC138298,SCYB4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A

CXCL4分子背景

CXCL4, or Platelet factor 4 (PF4), is a small cytokine belonging to the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. CXCL4 is chemotactic for neutrophils and monocytes and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. CXCL4/PF4 is up-regulated in human liver fibrosis and that it plays a nonredundant, functional role in experimental liver fibrosis by mediating stellate cell proliferation, migration, and intrahepatic immune cell recruitment.

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