BST1

Bone marrow stromal cell antigen-1(BST-1) or CD157 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that belongs to the CD38 family. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth.BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.