Alpha-fetoprotein 靶点蛋白|抗体药物|临床药物信息

Alpha-fetoprotein信息

英文名称：Alpha-fetoprotein
中文名称：甲胎蛋白
靶点别称：Alpha-Fetoglobulin，AFP，Alpha-fetoprotein，Alpha Fetoprotein，Alpha-1-Fetoprotein，HPAFP，AFPD，FETA，alpha-Fetoproteins

上市药物数量：0
临床药物数量：6
最高研发阶段：临床二期

Alpha-fetoprotein产品列表

筛选结果

产品库

在线 (1)

物种

Human (1)

标签

His Tag (1)

属性

Protein (1)

标记

Unconjugated (1)

货号	物种	产品描述	蛋白结构	纯度	活性
ALN-H52H9	Human	Human Alpha-fetoprotein, His Tag

Alpha-fetoprotein 分子别名

Alpha-fetoprotein

Alpha-fetoprotein 分子背景

Alpha-fetoprotein(AFP) is the first tumor marker with clinical application value found by human. AFP has an ability to induce the immune escapes through inhibiting the function of dendritic cells, natural killer cells, and T lymphocytes. By in vitro modification, the immunogenicity and immune response of AFP could be enhanced. AFP-modified immune cell vaccine or peptide vaccine has displayed the specific antitumor immunity against AFP-positive tumor cells and laid a better foundation for the immunotherapy of liver cancer. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Alpha-fetoprotein 前沿进展

Alpha-fetoprotein临床药物信息

英文名称	研发代码	研发阶段	公司	适应症	临床试验
JWATM-203	JWATM-203; JWATM203	临床二期	苏州药明巨诺生物科技有限公司	肝细胞癌	详情
Alpha fetoprotein targeted T-cell therapy (Adaptimmune)	AFP TCR (ADP-A2AFP); ADP-A2AFP; AFP TCR; AFPc332T	临床一期	Adaptimmune Llc	肝癌	详情
ET1402L1-CART	AFP/ET-1402; ET1402; ET-1402; AFP-CAR; ET-140202	临床一期	Eureka Therapeutics Inc	肝癌, 肝细胞癌	详情
CPU-118	CPU-118	临床一期	中国药科大学	肝癌, 实体瘤	详情
TAEST-1901	TAEST-1901	临床一期	香雪生命科学技术（广东）有限公司	肝癌, 肿瘤	详情
SynOV1.1		临床二期	北京合生基因科技有限公司	实体瘤, 肝细胞癌	详情

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