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Alpha-fetoprotein信息

英文名称:Alpha-fetoprotein
中文名称:甲胎蛋白
靶点别称:Alpha-Fetoglobulin,AFP,Alpha-fetoprotein,Alpha Fetoprotein,Alpha-1-Fetoprotein,HPAFP,AFPD,FETA,alpha-Fetoproteins
上市药物数量:0
临床药物数量:7
最高研发阶段:临床二期

Alpha-fetoprotein产品列表

产品库
物种
标签
属性
货号 物种 产品描述 蛋白结构 纯度 活性
ALN-H52H9
Human
Human Alpha-fetoprotein, His Tag
 
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Alpha-fetoprotein 分子别名

Alpha-fetoprotein

Alpha-fetoprotein 分子背景

Alpha-fetoprotein(AFP) is the first tumor marker with clinical application value found by human. AFP has an ability to induce the immune escapes through inhibiting the function of dendritic cells, natural killer cells, and T lymphocytes. By in vitro modification, the immunogenicity and immune response of AFP could be enhanced. AFP-modified immune cell vaccine or peptide vaccine has displayed the specific antitumor immunity against AFP-positive tumor cells and laid a better foundation for the immunotherapy of liver cancer. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Alpha-fetoprotein 前沿进展

Alpha-fetoprotein临床药物信息

英文名称 研发代码 研发阶段 公司 适应症 临床试验
ADP-A2AFP AFPc332T 临床一期 Adaptimmune Therapeutics Plc 肝细胞癌 详情
JWATM-203 JWATM-203; JWATM203 临床二期 苏州药明巨诺生物科技有限公司 肝细胞癌 详情
TAEST-1901 TAEST-1901 临床一期 肝癌, 肿瘤 详情
SynOV1.1 临床二期 北京合生基因科技有限公司 实体瘤, 肝细胞癌 详情
ET1402L1-ARTEMIS T cells 颐昂生物科技(北京)有限公司 详情
ET1402L1-CART AFP-CAR; ET-140202; AFP/ET-1402; ET1402; ET-1402 优瑞科 详情
CPU-118 CPU-118 临床一期 中国药科大学 肝癌, 实体瘤 详情
Alpha fetoprotein targeted T-cell therapy (Adaptimmune) AFP TCR (ADP-A2AFP); ADP-A2AFP; AFP TCR 临床一期 Adaptimmune 肝癌 详情

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